SCHEMBL19445637 — predicted protein targets

Predicted protein targets (top 12)

	gene	UniProt	supporting neighbours	confidence
▸	KLKB1	P03952	1/20	0.40

▸	MMP2	P08253	2/20	0.39

▸	TSHR	P16473	1/20	0.37

▸	ERAP2	Q6P179	7/20	0.37

▸	LNPEP	Q9UIQ6	6/20	0.37

▸	ERAP1	Q9NZ08	3/20	0.37

▸	HDAC1	Q13547	1/20	0.37

▸	PDF	Q9HBH1	1/20	0.36

▸	HDAC4	P56524	1/20	0.35

▸	MEF2D	Q14814	1/20	0.35

▸	KCNB1	Q14721	1/20	0.35

▸	KMT2A	Q03164	1/20	0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12515368	0.88	KLKB1 (0.41)	KLKB1MMP2TSHRERAP2LNPEP
SCHEMBL19445715	0.87	KLKB1 (0.41)	KLKB1MMP2TSHRERAP2LNPEP
SCHEMBL21371597	0.87	KLKB1 (0.41)	KLKB1MMP2TSHRERAP2LNPEP
SCHEMBL19445764	0.85	KLKB1 (0.40)	KLKB1MMP2TSHRERAP2LNPEP
SCHEMBL19445640	0.85	MMP2 (0.41)	KLKB1MMP2TSHRERAP2LNPEP
SCHEMBL19445603	0.85	KLKB1 (0.39)	KLKB1MMP2TSHRERAP2LNPEP
SCHEMBL19445630	0.81	LNPEP (0.48)	MMP2TSHRERAP2LNPEPERAP1
SCHEMBL19445611	0.81	NPC1 (0.38)	KLKB1MMP2TSHRERAP2LNPEP
SCHEMBL12516946	0.80	KLKB1 (0.42)	KLKB1MMP2TSHRERAP2LNPEP
SCHEMBL19445833	0.80	KLKB1 (0.42)	KLKB1MMP2TSHRERAP2LNPEP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
EP-2709619-B1	COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS	CELLCEUTIX CORP (US)	2017-10-11	—	—	EP	disclosed