Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.38 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 4/20 | 0.35 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.34 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.34 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.34 |
| ▸ | PSMA1 | P25786 | 1/20 | 0.34 |
| ▸ | PSMA2 | P25787 | 1/20 | 0.34 |
| ▸ | PSMA3 | P25788 | 1/20 | 0.34 |
| ▸ | PSMA4 | P25789 | 1/20 | 0.34 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.34 |
| ▸ | PSMB9 | P28065 | 1/20 | 0.34 |
| ▸ | PSMA5 | P28066 | 1/20 | 0.34 |
| ▸ | PSMB4 | P28070 | 1/20 | 0.34 |
| ▸ | PSMB6 | P28072 | 1/20 | 0.34 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.34 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.34 |
| ▸ | PSMB3 | P49720 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19445603 | 0.94 | KLKB1 (0.39) | KLKB1MMP2TSHRERAP2HDAC4 | |
| SCHEMBL19445810 | 0.86 | KCNB1 (0.40) | KLKB1MMP2TSHRERAP2LNPEP | |
| SCHEMBL19445641 | 0.85 | ERAP2 (0.44) | TERTKLKB1MMP2ERAP2LNPEP | |
| SCHEMBL19445879 | 0.85 | KCNK3 (0.41) | NPC1KLKB1MMP2TSHRKCNB1 | |
| SCHEMBL19445834 | 0.84 | MMP2 (0.39) | KLKB1MMP2TSHRKCNB1HDAC1 | |
| SCHEMBL12515368 | 0.83 | KLKB1 (0.41) | KLKB1MMP2TSHRERAP2HDAC4 | |
| SCHEMBL19445616 | 0.83 | ALDH1A1 (0.40) | ALDH1A1 | |
| SCHEMBL19445764 | 0.83 | KLKB1 (0.40) | KLKB1MMP2TSHRERAP2HDAC4 | |
| SCHEMBL19445715 | 0.82 | KLKB1 (0.41) | KLKB1MMP2TSHRERAP2HDAC4 | |
| SCHEMBL21371597 | 0.82 | KLKB1 (0.41) | KLKB1MMP2TSHRERAP2HDAC4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2709619-B1 | COMPOUNDS FOR USE IN TREATMENT OF MUCOSITIS | CELLCEUTIX CORP (US) | 2017-10-11 | — | — | EP | disclosed |