Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 18/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | FPR3 | P25089 | 1/20 | 0.35 |
| ▸ | TSPO | P30536 | 1/20 | 0.35 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.35 |
| ▸ | IGLV6-57 | P01721 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23459716 | 0.88 | KDM4E (0.41) | CRHR1KDM4EALDH1A1 | |
| SCHEMBL19447026 | 0.73 | CRHR1 (0.40) | CRHR1FPR3TSPOTMEM97 | |
| SCHEMBL12871103 | 0.67 | TDP1 (0.44) | CRHR1ALDH1A1 | |
| SCHEMBL14259222 | 0.66 | TDP1 (0.50) | KDM4EALDH1A1 | |
| SCHEMBL694204 | 0.64 | NOS3 (0.41) | KDM4EALDH1A1 | |
| SCHEMBL25946214 | 0.63 | CRHR1 (0.41) | CRHR1 | |
| SCHEMBL20693396 | 0.63 | CRHR1 (0.39) | CRHR1 | |
| SCHEMBL11580628 | 0.62 | S100B (0.53) | CRHR1ALDH1A1IGLV6-57 | |
| SCHEMBL20693351 | 0.61 | IGLV6-57 (0.41) | CRHR1KDM4EALDH1A1TSPOIGLV6-57 | |
| SCHEMBL17706659 | 0.60 | MAPT (0.57) | CRHR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2565182-B1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-10-11 | — | — | EP | disclosed |