Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRHR1 | P34998 | 19/20 | 0.40 |
| ▸ | NOS3 | P29474 | 1/20 | 0.38 |
| ▸ | NOS1 | P29475 | 1/20 | 0.38 |
| ▸ | NOS2 | P35228 | 1/20 | 0.38 |
| ▸ | FPR3 | P25089 | 2/20 | 0.36 |
| ▸ | TSPO | P30536 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12250799 | 0.89 | NOS3 (0.43) | CRHR1NOS3NOS1NOS2 | |
| SCHEMBL12250797 | 0.76 | NOS3 (0.42) | NOS3NOS1NOS2 | |
| SCHEMBL19446974 | 0.73 | CRHR1 (0.38) | CRHR1FPR3TSPOTMEM97 | |
| SCHEMBL12810688 | 0.70 | NOS3 (0.36) | CRHR1NOS3NOS1NOS2 | |
| SCHEMBL17696428 | 0.70 | ALOX15 (0.33) | NOS3NOS1NOS2 | |
| SCHEMBL17532955 | 0.70 | PGK1 (0.39) | CRHR1TDP1 | |
| SCHEMBL15061923 | 0.70 | NOS3 (0.54) | NOS3NOS1NOS2 | |
| SCHEMBL21388440 | 0.69 | HCAR3 (0.50) | CRHR1NOS3NOS2 | |
| SCHEMBL26296867 | 0.69 | MAPT (0.39) | CRHR1 | |
| SCHEMBL12250798 | 0.68 | NOS3 (0.42) | NOS3NOS1NOS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2565182-B1 | NOVEL AMIDE DERIVATIVE AND USE THEREOF AS MEDICINE | MITSUBISHI TANABE PHARMA CORP (JP) | 2017-10-11 | — | — | EP | disclosed |