Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV3 | Q8NET8 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.34 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.34 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17518816 | 0.73 | TRPV3 (0.44) | TRPV3KCNH2KDM5BMAP4K4PIK3CA | |
| SCHEMBL19390317 | 0.73 | KCNH2 (0.41) | TRPV3KCNH2KDM5BMAP4K4PIK3CA | |
| SCHEMBL16144649 | 0.72 | KCNH2 (0.45) | TRPV3KCNH2KDM5B | |
| SCHEMBL30641497 | 0.68 | TRPV4 (0.44) | TRPV3KCNH2KDM5BMAP4K4PIK3CA | |
| SCHEMBL1004952 | 0.64 | TRPV3 (0.46) | TRPV3KCNH2PIK3CA | |
| SCHEMBL2401818 | 0.62 | KDM4E (0.49) | — | |
| SCHEMBL28558708 | 0.62 | TRPV4 (0.48) | KCNH2 | |
| SCHEMBL2717177 | 0.62 | LDHA (0.40) | — | |
| SCHEMBL25212518 | 0.62 | TRPV4 (0.44) | TRPV3KCNH2MAP4K4PIK3CAMINK1 | |
| SCHEMBL28242130 | 0.62 | TRPV4 (0.44) | TRPV3KCNH2MAP4K4PIK3CAMINK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017175066-A1 | HETEROCYCLIC GPR119 AGONIST COMPOUNDS | MANKIND PHARMA LTD. (IN) | 2017-10-12 | — | — | WO | disclosed |