Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 7/20 | 0.52 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.50 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | PRKCI | P41743 | 1/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27724975 | 1.00 | TBXAS1 (0.52) | TBXAS1CYP19A1EGLN3KDM4EALDH1A1 | |
| Bicarbonate SCHEMBL28981668 | 0.92 | TBXAS1 (0.56) | TBXAS1CYP19A1EGLN3ALDH1A1LMNA | |
| SCHEMBL11959516 | 0.89 | TBXAS1 (0.58) | TBXAS1CYP19A1KDM4EPRKCIQPCT | |
| SCHEMBL28694303 | 0.87 | TBXAS1 (0.55) | TBXAS1CYP19A1EGLN3KDM4EALDH1A1 | |
| SCHEMBL18873533 | 0.86 | TBXAS1 (0.64) | TBXAS1 | |
| SCHEMBL23948110 | 0.84 | TBXAS1 (0.61) | TBXAS1CYP19A1KDM4EPRKCIQPCT | |
| SCHEMBL1223641 | 0.82 | TBXAS1 (0.64) | TBXAS1CYP19A1PRKCIQPCT | |
| SCHEMBL439530 | 0.82 | TBXAS1 (0.56) | TBXAS1CYP19A1EGLN3PRKCIALOX15 | |
| SCHEMBL7285764 | 0.81 | CYP19A1 (0.47) | TBXAS1CYP19A1EGLN3PRKCIALOX15 | |
| SCHEMBL2232319 | 0.81 | TBXAS1 (0.67) | TBXAS1CYP19A1QPCT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170295792-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | CORTEVA AGRISCIENCE LLC | 2017-10-19 | — | — | US | disclosed |
| US-20170290333-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | CORTEVA AGRISCIENCE LLC | 2017-10-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170290333-A1 | PICOLINAMIDE COMPOUNDS WITH FUNGICIDAL ACTIVITY | PFAS, CASP2, CYP1A2 | TBXAS1 3406/4885CYP19A1 121/4885EGLN3 592/4885 |
| US-20170295792-A1 | USE OF PICOLINAMIDE COMPOUNDS AS FUNGICIDES | PFAS, FKBP2, FKBP14 | TBXAS1 3633/4885CYP19A1 71/4885EGLN3 549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.