Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.50 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.44 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | ESR1 | P03372 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.39 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.39 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.39 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.39 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10092625 | 0.93 | CYP17A1 (0.52) | PLA2G10PLA2G2AKMT2AADRA2AADRA2B | |
| SCHEMBL15893699 | 0.82 | LOXL2 (0.60) | F10LOXL2HDAC6 | |
| SCHEMBL13362346 | 0.82 | PRSS1 (0.60) | PLA2G10PLA2G2ATSHRPRSS1PRSS2 | |
| SCHEMBL14565742 | 0.80 | SMN1; SMN2 (0.61) | ALDH1A1TDP1PRSS1SMN1; SMN2CA2 | |
| SCHEMBL22872694 | 0.80 | NOS1 (0.52) | KMT2AALDH1A1CYP3A4LMNALOXL2 | |
| SCHEMBL451895 | 0.77 | PLA2G10 (0.53) | PLA2G10PLA2G2AKMT2AADRA2AADRA2B | |
| SCHEMBL20117499 | 0.77 | THRB (0.53) | KMT2AALDH1A1ESR1ESR2SMN1; SMN2 | |
| SCHEMBL18726920 | 0.75 | PLA2G10 (0.33) | PLA2G10PLA2G2ACYP17A1 | |
| SCHEMBL8178806 | 0.75 | CYP2C9 (0.37) | KMT2AALDH1A1PRSS1PRSS2PRSS3 | |
| SCHEMBL7134591 | 0.74 | PLA2G10 (0.83) | PLA2G10PLA2G2AKMT2AALDH1A1CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017174879-A1 | COMPOUNDS FOR USE IN THE TREATMENT OF CANCER | UNIVERSITY OF OULU (FI) | 2017-10-12 | — | — | WO | disclosed |