Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 2/20 | 0.33 |
| ▸ | MAOB | P27338 | 2/20 | 0.33 |
| ▸ | F10 | P00742 | 1/20 | 0.33 |
| ▸ | LOXL2 | Q9Y4K0 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | NOS1 | P29475 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10209044 | 0.79 | PLA2G10 (0.52) | CYP2C9CYP2C19ALDH1A1MAOAMAOB | |
| SCHEMBL10211024 | 0.79 | PRSS1 (0.57) | F10LOXL2PRSS1PRSS2PRSS3 | |
| SCHEMBL22872694 | 0.79 | NOS1 (0.52) | CYP2C19ALDH1A1LOXL2MAPTEPHX2 | |
| SCHEMBL14538021 | 0.76 | SMN1; SMN2 (0.39) | ALDH1A1EPHX2NR1H4KMT2ASMN1; SMN2 | |
| SCHEMBL19457426 | 0.75 | PLA2G10 (0.50) | CYP2C9ALDH1A1F10LOXL2PRSS1 | |
| SCHEMBL14542686 | 0.75 | ADH1B (0.52) | CYP2C9CYP2C19ALDH1A1MAPTRAB9A | |
| SCHEMBL15893699 | 0.73 | LOXL2 (0.60) | F10LOXL2NOS1NOS2NOS3 | |
| SCHEMBL13362346 | 0.73 | PRSS1 (0.60) | F10LOXL2EPHX2PRSS1PRSS2 | |
| SCHEMBL17742304 | 0.72 | ALDH1A1 (0.63) | ALDH1A1POLBMAPTEPHX2NR1H4 | |
| SCHEMBL14565742 | 0.71 | SMN1; SMN2 (0.61) | ALDH1A1PRSS1CA2SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008063670-A1 | HETEROBICYCLIC MATRIX METALLOPROTEASE INHIBITORS | ALANTOS PHARMACEUTICALS HOLDING, INC. (US) | 2008-05-29 | — | — | WO | disclosed |