Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.44 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.43 |
| ▸ | ZDHHC2 | Q9UIJ5 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.42 |
| ▸ | GRIK2 | Q13002 | 3/20 | 0.42 |
| ▸ | GSR | P00390 | 2/20 | 0.42 |
| ▸ | GRM8 | O00222 | 1/20 | 0.42 |
| ▸ | GRM6 | O15303 | 1/20 | 0.42 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.42 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | GRM5 | P41594 | 1/20 | 0.42 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.42 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.42 |
| ▸ | GRIA3 | P42263 | 1/20 | 0.42 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19463173 | 1.00 | ALDH1A1 (0.45) | ALDH1A1TSHRMAPK1TDP1DDAH1 | |
| SCHEMBL19463086 | 0.89 | DDAH1 (0.56) | ALDH1A1TSHRMAPK1TDP1DDAH1 | |
| SCHEMBL19463087 | 0.89 | DDAH1 (0.56) | ALDH1A1TSHRMAPK1TDP1DDAH1 | |
| SCHEMBL20445992 | 0.87 | ZDHHC20 (0.51) | DDAH1ZDHHC20ZDHHC2GSROTC | |
| SCHEMBL20446016 | 0.87 | ZDHHC20 (0.51) | DDAH1ZDHHC20ZDHHC2GSROTC | |
| SCHEMBL10507212 | 0.87 | ZDHHC20 (0.51) | DDAH1ZDHHC20ZDHHC2GSROTC | |
| SCHEMBL6817462 | 0.87 | ZDHHC20 (0.51) | DDAH1ZDHHC20ZDHHC2GSROTC | |
| SCHEMBL20446014 | 0.86 | DDAH1 (0.50) | DDAH1ZDHHC20ZDHHC2GSROTC | |
| SCHEMBL22199690 | 0.84 | SLC1A1 (0.44) | ALDH1A1TSHRMAPK1TDP1DDAH1 | |
| SCHEMBL28463935 | 0.82 | TSHR (0.50) | ALDH1A1TSHRMAPK1TDP1DDAH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10954287-B2 | Ras binding peptides and methods of use | RA PHARMACEUTICALS, INC. (US) | 2021-03-23 | — | — | US | disclosed |
| US-20190119358-A1 | RAS BINDING PEPTIDES AND METHODS OF USE | RA PHARMACEUTICALS, INC. | 2019-04-25 | — | — | US | disclosed |
| EP-3442991-A1 | RAS BINDING PEPTIDES AND METHODS OF USE | RA Pharmaceuticals, Inc. (US) | 2019-02-20 | — | — | EP | disclosed |
| WO-2017181061-A1 | RAS BINDING PEPTIDES AND METHODS OF USE | RA PHARMACEUTICALS, INC. (US) | 2017-10-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10954287-B2 | Ras binding peptides and methods of use | KRAS, RASGRP1, NRAS | ALDH1A1 4777/4885TSHR 1416/4885MAPK1 248/4885 |
| US-20190119358-A1 | RAS BINDING PEPTIDES AND METHODS OF USE | KRAS, RASGRP1, NRAS | ALDH1A1 4777/4885TSHR 1416/4885MAPK1 248/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.