SCHEMBL194650

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL193998	0.89	AR (0.46)	VDRARALDH1A1LMNAKDM4E
	SCHEMBL23895825	0.89	ALDH1A1 (0.46)	ALDH1A1LMNAKDM4EMEN1GAA
	SCHEMBL12735969	0.88	VDR (0.44)	VDRARALDH1A1LMNAKDM4E
	SCHEMBL29330676	0.85	ALDH1A1 (0.51)	ALDH1A1LMNAKDM4EMEN1GAA
	SCHEMBL195146	0.85	ALDH1A1 (0.43)	VDRARALDH1A1LMNAKDM4E
	SCHEMBL24436451	0.84	ALDH1A1 (0.45)	VDRARALDH1A1LMNAKDM4E
	SCHEMBL22222289	0.83	ALDH1A1 (0.44)	ALDH1A1LMNAKDM4EMEN1GAA
	SCHEMBL23895816	0.83	ALDH1A1 (0.42)	ALDH1A1LMNAKDM4EMEN1GAA
	SCHEMBL22435316	0.83	VDR (0.42)	VDRALDH1A1LMNAKDM4EMEN1
	SCHEMBL22435239	0.83	VDR (0.42)	VDRALDH1A1LMNAKDM4EMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.