SCHEMBL194730

SCHEMBL194730

O=C(CBr)c1ccccc1NNc1ccccc1C(=O)CBr

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTPN1 P18031 6/20 0.53
GSK3B P49841 5/20 0.48
HPGDS O60760 1/20 0.42
KDM4E B2RXH2 4/20 0.41
AGTR1 P30556 1/20 0.41
RAB9A P51151 1/20 0.41
ALDH1A1 P00352 3/20 0.38
HPGD P15428 3/20 0.38
KMT2A Q03164 2/20 0.38
HSD17B10 Q99714 1/20 0.38
LMNA P02545 2/20 0.37
POLB P06746 1/20 0.37
ATM Q13315 1/20 0.37
NPC1 O15118 1/20 0.37
TP53 P04637 1/20 0.37
GAA P10253 1/20 0.37
HTT P42858 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
MEN1 O00255 1/20 0.37
CYP3A4 P08684 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10396219 0.84 PTPN1 (0.50) PTPN1GSK3BKDM4ERAB9AALDH1A1
SCHEMBL9409754 0.82 PTPN1 (0.65) PTPN1GSK3BHPGDSKDM4EALDH1A1
SCHEMBL980175 0.81 CYP2C19 (0.59) PTPN1KDM4ERAB9AALDH1A1HPGD
SCHEMBL9624082 0.78 KMT2A (0.59) PTPN1KDM4EALDH1A1HPGDKMT2A
SCHEMBL9732721 0.78 BACE1 (0.57) PTPN1GSK3BRAB9AHPGDKMT2A
SCHEMBL29758522 0.74 PTPN1 (0.57) PTPN1GSK3BHPGDSKDM4ERAB9A
SCHEMBL166468 0.74 PTPN1 (0.57) PTPN1GSK3BHPGDSKDM4ERAB9A
SCHEMBL1701142 0.74 PTPN1 (0.57) PTPN1GSK3BKDM4ERAB9AALDH1A1
SCHEMBL31519376 0.74 ALDH1A1 (0.64) PTPN1GSK3BHPGDSKDM4EALDH1A1
SCHEMBL29845700 0.74 PTPN1 (0.57) PTPN1GSK3BKDM4ERAB9AALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 179 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260126453-A1 Mass Spectrometry Kit Including a Cross-linked Antibody or Fragment Thereof THE BINDING SITE GROUP LTD (GB) 2026-05-07 US disclosed
EP-4675278-A2 ASSAY FOR PLASMA CELL ASSOCIATED DISEASE The Binding Site Group Limited (GB) 2026-01-07 EP disclosed
US-12461108-B2 Mass spectrometry kit including a cross-linked antibody or fragment thereof THE BINDING SITE GROUP LIMITED (GB) 2025-11-04 US disclosed
US-20240148882-A1 METHODS OF TREATING AN OCULAR DISEASE OR DISORDER THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2024-05-09 US disclosed
US-20230391851-A1 ANTIBODIES THE BINDING SITE GROUP LIMITED (GB) 2023-12-07 US disclosed
US-11723982-B2 Methods of treating an ocular disease or disorder THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 2023-08-15 US disclosed
EP-3420362-B1 ANTIBODIES THE BINDING SITE GROUP LTD (GB) 2023-03-22 EP disclosed
US-20230080943-A1 ASSAY FOR PLASMA CELL ASSOCIATED DISEASE THE BINDING SITE GROUP LIMITED (GB) 2023-03-16 US disclosed
EP-4123308-A1 MASS SPECTROMETRY KIT The Binding Site Group Limited (GB) 2023-01-25 EP disclosed
EP-3420361-B1 MASS SPECTROMETRY KIT THE BINDING SITE GROUP LTD (GB) 2023-01-04 EP disclosed
US-20040126838-A1 Follicle stimulating hormone: remodeling and glycoconjugation of FSH NEOSE TECHNOLOGIES, INC. 2004-07-01 US disclosed
US-20040115168-A1 Interferon beta: remodeling and glycoconjugation of interferon beta NEOSE TECHNOLOGIES, INC. 2004-06-17 US disclosed
US-20040082026-A1 Interferon alpha: remodeling and glycoconjugation of interferon alpha NEOSE TECHNOLOGIES, INC. 2004-04-29 US disclosed
US-20040077836-A1 Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF NEOSE TECHNOLOGIES, INC. 2004-04-22 US disclosed
US-20040063911-A1 Protein remodeling methods and proteins/peptides produced by the methods NEOSE TECHNOLOGIES, INC. 2004-04-01 US disclosed
US-20040043446-A1 Alpha galalctosidase a: remodeling and glycoconjugation of alpha galactosidase A NEOSE TECHNOLOGIES, INC. 2004-03-04 US disclosed
US-20040001892-A1 Tunable, semi-interpenetrating polymer networks (sIPNS) for medicine and biotechnology THE REGENTS OF THE UNIVERSITY OF CALIFORNIA 2004-01-01 US disclosed
US-5965106-A ADMINISTERING TARGETING MOIETY COUPLED TO AFFINITY COMPONENT, WHEREIN TARGETING MOIETY HAS AFFINITY FOR BINDING SITES IN TARGET AREA, AND BINDING PARTNER TO AFFINITY COMPONENT COUPLED TO FUNCTIONAL MOIETY TO LOCALIZE FUNCTIONAL MOIETY IN TARGET PERIMMUNE HOLDINGS, INC. (US) 1999-10-12 US disclosed
EP-0562624-A2 Stabilization of functional proteins Modrovich, Ivan E. (US) 1993-09-29 EP disclosed
US-4202775-A CROSSLINKABLE ETHYLENICALLY UNSATURATED POROUS COPOLYMER ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1980-05-13 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260126453-A1 Mass Spectrometry Kit Including a Cross-linked Antibody or Fragment Thereof IGLV6-57, IGSF11, FCGR3B PTPN1 466/4885GSK3B 4491/4885HPGDS 2393/4885
US-20040077836-A1 Granulocyte colony stimulating factor: remodeling and glycoconjugation of G-CSF CSF3R, CSF1R, GMFG PTPN1 1110/4885GSK3B 4541/4885HPGDS 173/4885
US-20040082026-A1 Interferon alpha: remodeling and glycoconjugation of interferon alpha IFNG, IFNAR1, IRF3 PTPN1 463/4885GSK3B 3333/4885HPGDS 288/4885
US-20040063911-A1 Protein remodeling methods and proteins/peptides produced by the methods PTMS, ANPEP, SMURF1 PTPN1 1812/4885GSK3B 4308/4885HPGDS 2601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.