Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5 | P09917 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 8/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NPC1 | O15118 | 6/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | ATM | Q13315 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.42 |
| ▸ | NFKB1 | P19838 | 2/20 | 0.42 |
| ▸ | NFKB2 | Q00653 | 2/20 | 0.42 |
| ▸ | RELA | Q04206 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4036753 | 0.82 | ALDH1A1 (0.55) | RAB9AMAPTALDH1A1NPC1KDM4E | |
| SCHEMBL19475521 | 0.82 | RAB9A (0.49) | RAB9AMAPTALDH1A1NPC1KDM4E | |
| SCHEMBL9427325 | 0.78 | ALDH1A1 (0.48) | ALOX5RAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL9428612 | 0.77 | PTGS2 (0.51) | ALOX5RAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL13140274 | 0.77 | FFAR1 (0.53) | ALOX5RAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL41221 | 0.77 | LMNA (0.51) | ALOX5RAB9AMAPTL3MBTL1GAA | |
| SCHEMBL6527094 | 0.77 | RAB9A (0.62) | RAB9AMAPTALDH1A1NPC1KDM4E | |
| SCHEMBL9427556 | 0.76 | RAB9A (0.49) | ALOX5RAB9AMAPTALDH1A1NPC1 | |
| SCHEMBL4034509 | 0.76 | RAB9A (0.56) | RAB9AMAPTALDH1A1NPC1KDM4E | |
| SCHEMBL4039765 | 0.76 | CYSLTR1 (0.53) | RAB9AMAPTALDH1A1NPC1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184520-A1 | SUBSTITUTED AND FUSED 6-MEMBERED PROTEASE ACTIVATED RECEPTOR 4 (PAR-4) ANTAGONISTS | VANDERBILT UNIVERSITY (US) | 2017-10-26 | — | — | WO | disclosed |