Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | CD4 | P01730 | 2/20 | 0.54 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HTR2A | P28223 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | HTR6 | P50406 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | ACHE | P22303 | 1/20 | 0.47 |
| ▸ | BACE1 | P56817 | 1/20 | 0.47 |
| ▸ | DRD2 | P14416 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14166152 | 0.95 | SMN1; SMN2 (0.56) | SMN1; SMN2CD4SORT1LMNAHTR2A | |
| SCHEMBL1943416 | 0.91 | ACHE (0.53) | SMN1; SMN2CD4SORT1POLBHTR6 | |
| SCHEMBL8540877 | 0.88 | HTR6 (0.54) | SMN1; SMN2CD4SORT1LMNAALDH1A1 | |
| SCHEMBL8540875 | 0.88 | HTR6 (0.54) | SMN1; SMN2CD4SORT1LMNAALDH1A1 | |
| SCHEMBL9212450 | 0.88 | BCHE (0.50) | SMN1; SMN2CD4SORT1LMNAALDH1A1 | |
| SCHEMBL9208266 | 0.82 | BCHE (0.58) | HTR2AALDH1A1POLBHTR6ACHE | |
| SCHEMBL5744572 | 0.80 | CYP2D6 (0.57) | SMN1; SMN2CD4SORT1LMNAHTR2A | |
| SCHEMBL7782471 | 0.80 | HTR6 (0.53) | SMN1; SMN2CD4SORT1LMNAALDH1A1 | |
| SCHEMBL9217317 | 0.79 | HTR2A (0.55) | HTR2AALDH1A1HTR6ACHEDRD2 | |
| SCHEMBL19475555 | 0.79 | GRIN2B (0.57) | SMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184549-A1 | PYRROLOPYRIDINE RETINOIC ACID RECEPTOR-RELATED ORPHAN RECEPTOR MODULATORS AND USES THEREOF | INNOV17 LLC (US) | 2017-10-26 | — | — | WO | disclosed |