Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | MEN1 | O00255 | 4/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3085481 | 0.94 | ALDH1A1 (0.42) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL29814681 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL1697611 | 0.85 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL28587025 | 0.83 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL14552838 | 0.80 | TSHR (0.41) | MEN1KMT2AGAALMNASMN1; SMN2 | |
| SCHEMBL22578680 | 0.79 | MEN1 (0.46) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL12797797 | 0.79 | ALDH1A1 (0.44) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL194837 | 0.78 | MEN1 (0.54) | ALDH1A1MEN1KMT2AMAPTNPC1 | |
| SCHEMBL28667060 | 0.78 | ALDH1A1 (0.50) | ALDH1A1MEN1KMT2AMAPTL3MBTL1 | |
| SCHEMBL10296061 | 0.78 | ALDH1A1 (0.49) | ALDH1A1MEN1KMT2AMAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1732895-B1 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2016-11-16 | — | — | EP | disclosed |
| US-8513462-B2 | Pesticides and uses thereof | DOW AGROSCIENCES LLC (US) | 2013-08-20 | — | — | US | disclosed |
| US-8513462-B2 | Pesticides and uses thereof | DOW AGROSCIENCES LLC (US) | 2013-08-20 | — | — | US | disclosed |
| US-20130012385-A1 | PESTICIDES AND USES THEREOF | DOW AGROSCIENCES LLC (US) | 2013-01-10 | — | — | US | disclosed |
| US-20130012385-A1 | PESTICIDES AND USES THEREOF | DOW AGROSCIENCES LLC (US) | 2013-01-10 | — | — | US | disclosed |
| US-8288589-B2 | Pesticides and uses thereof | DOW AGROSCIENCES, LLC (US) | 2012-10-16 | — | — | US | disclosed |
| US-8288589-B2 | Pesticides and uses thereof | DOW AGROSCIENCES, LLC (US) | 2012-10-16 | — | — | US | disclosed |
| US-8183268-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES, LLC. (US) | 2012-05-22 | — | — | US | disclosed |
| US-8183268-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES, LLC. (US) | 2012-05-22 | — | — | US | disclosed |
| US-8183268-B2 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | DOW AGROSCIENCES, LLC. (US) | 2012-05-22 | — | — | US | disclosed |
| WO-2008057131-A1 | HETEROARYL (SUBSTITUTED) ALKYL N-SUBSTITUTED SULFOXIMINES AS INSECTICIDES | DOW AGROSCIENCES LLC (US) | 2008-05-15 | — | — | WO | disclosed |
| US-20080108665-A1 | Use of N-substituted sulfoximines for control of invertebrate pests | DOW AGROSCIENCES LLC | 2008-05-08 | — | — | US | disclosed |
| US-20080108665-A1 | Use of N-substituted sulfoximines for control of invertebrate pests | DOW AGROSCIENCES LLC | 2008-05-08 | — | — | US | disclosed |
| US-20080108665-A1 | Use of N-substituted sulfoximines for control of invertebrate pests | DOW AGROSCIENCES LLC | 2008-05-08 | — | — | US | disclosed |
| US-20080108666-A1 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | CORTEVA AGRISCIENCE LLC | 2008-05-08 | — | — | US | disclosed |
| US-20080108666-A1 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | CORTEVA AGRISCIENCE LLC | 2008-05-08 | — | — | US | disclosed |
| US-20080108666-A1 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | CORTEVA AGRISCIENCE LLC | 2008-05-08 | — | — | US | disclosed |
| EP-1732895-A2 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | Dow Agrosciences LLC (US) | 2006-12-20 | — | — | EP | disclosed |
| WO-2006060029-A2 | INSECTICIDAL N-SUBSTITUTED SULFOXIMINES | DOW AGROSCIENCES LLC (US) | 2006-06-08 | — | — | WO | disclosed |
| US-20050228027-A1 | Insecticidal N-substituted sulfoximines | CORTEVA AGRISCIENCE LLC | 2005-10-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130012385-A1 | PESTICIDES AND USES THEREOF | ACHE, DDT, BCHE | ALDH1A1 820/4885MEN1 4050/4885KMT2A 2226/4885 |
| US-20080108666-A1 | Heteroaryl (substituted)alkyl N-substituted sulfoximines as insecticides | STS, DDT, TST | ALDH1A1 2819/4885MEN1 3884/4885KMT2A 143/4885 |
| US-20080108665-A1 | Use of N-substituted sulfoximines for control of invertebrate pests | SMOX, DDT, TST | ALDH1A1 2424/4885MEN1 3378/4885KMT2A 708/4885 |
| US-20050228027-A1 | Insecticidal N-substituted sulfoximines | GSS, STS, SMS | ALDH1A1 3325/4885MEN1 3396/4885KMT2A 861/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.