Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1948850 | 0.90 | LMNA (0.32) | LMNASMN1; SMN2 | |
| SCHEMBL1947496 | 0.85 | LMNA (0.33) | LMNASMN1; SMN2 | |
| SCHEMBL6525145 | 0.85 | LMNA (0.32) | LMNASMN1; SMN2 | |
| SCHEMBL17237651 | 0.81 | POLB (0.32) | LMNASMN1; SMN2 | |
| SCHEMBL1949941 | 0.80 | LMNA (0.34) | LMNASMN1; SMN2 | |
| SCHEMBL1950277 | 0.78 | MMP2 (0.32) | LMNASMN1; SMN2 | |
| SCHEMBL1948093 | 0.77 | MLYCD (0.35) | LMNASMN1; SMN2 | |
| SCHEMBL1439329 | 0.77 | AR (0.32) | LMNASMN1; SMN2 | |
| SCHEMBL1947566 | 0.77 | LMNA (0.32) | LMNASMN1; SMN2 | |
| SCHEMBL1948424 | 0.77 | ADRB2 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110135650-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | MERCK SHARP & DOHME LLC | 2011-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110135650-A1 | MORPHOLINONE COMPOUNDS AS FACTOR IXA INHIBITORS | SERPINC1, F9, F8 | LMNA 95/4885SMN1; SMN2 1538/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.