SCHEMBL194890

SCHEMBL194890

O=C(OC[CH]O)c1ccccc1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 2/20 0.59
MAPK1 P28482 1/20 0.57
HIF1A Q16665 1/20 0.57
SLC6A2 P23975 1/20 0.57
SLC6A3 Q01959 1/20 0.57
KMT2A Q03164 1/20 0.57
LMNA P02545 3/20 0.55
ALDH1A1 P00352 2/20 0.55
F2 P00734 1/20 0.52
TSHR P16473 2/20 0.52
CYP1A2 P05177 1/20 0.50
CYP2C9 P11712 1/20 0.50
CYP2C19 P33261 1/20 0.50
L3MBTL1 Q9Y468 2/20 0.49
GAA P10253 2/20 0.49
KDM4E B2RXH2 1/20 0.49
RAB9A P51151 3/20 0.47
NPC1 O15118 2/20 0.47
HPGD P15428 1/20 0.47
PPARG P37231 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6276758 0.85 TDP1 (0.61) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL8078151 0.85 TDP1 (0.61) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL8522569 0.85 TDP1 (0.61) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL8522570 0.85 TDP1 (0.61) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL1030901 0.83 TDP1 (0.59) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL27475377 0.82 TDP1 (0.53) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL6507336 0.82 TDP1 (0.57) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL1219383 0.82 LMNA (0.58) TDP1MAPK1HIF1ASLC6A2SLC6A3
SCHEMBL11673722 0.82 TDP1 (0.57) TDP1MAPK1HIF1ASLC6A2SLC6A3
Benzene SCHEMBL28207781 0.82 CYP3A4 (0.69) TDP1MAPK1HIF1ASLC6A2SLC6A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 121 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11209734-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11209733-B2 Oxime ester photoinitiators BASF SE 2021-12-28 US disclosed
US-11204554-B2 Oxime ester photoinitiators BASF SE 2021-12-21 US disclosed
EP-3019473-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2020-02-19 EP disclosed
US-10488756-B2 Oxime ester photoinitiators BASF SE (DE) 2019-11-26 US disclosed
EP-3354641-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2019-07-17 EP disclosed
US-10234761-B2 Oxime ester photoinitiators BASF SE (DE) 2019-03-19 US disclosed
EP-2847167-B9 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2019-02-20 EP disclosed
EP-3354641-A1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2018-08-01 EP disclosed
EP-2847167-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2018-07-18 EP disclosed
US-20040170924-A1 Oxime ester photoiniators having a combined structure CIBA CORPORATION 2004-09-02 US disclosed
WO-2004050653-A2 OXIME ESTER PHOTOINITIATORS WITH HETEROAROMATIC GROUPS CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2004-06-17 WO disclosed
EP-1410109-A1 PHOTOSENSITIVE RESIN COMPOSITION Ciba SC Holding AG (CH) 2004-04-21 EP disclosed
EP-1395615-A1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE Ciba SC Holding AG (CH) 2004-03-10 EP disclosed
US-6596445-B1 Initiators for photopolymerization of radically polymerizable compounds CIBA SPECIALTY CHEMICALS CORPORATION 2003-07-22 US disclosed
WO-2003010602-A1 PHOTOSENSITIVE RESIN COMPOSITION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-02-06 WO disclosed
WO-2002100903-A1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-12-19 WO disclosed
US-20020020832-A1 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORP. 2002-02-21 US disclosed
US-20010012596-A1 For resist applications; thermostability, storage stability CIBA SPECIALTY CHEMICALS CORP. 2001-08-09 US disclosed
US-5663212-A Light-sensitive resin composition FUJI PHOTO FILM CO., LTD. (JP) 1997-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11209734-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 TDP1 3327/4885MAPK1 3939/4885HIF1A 1305/4885
US-10488756-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 TDP1 3327/4885MAPK1 3939/4885HIF1A 1305/4885
US-11204554-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 TDP1 3339/4885MAPK1 3920/4885HIF1A 1358/4885
US-10234761-B2 Oxime ester photoinitiators C9, C5, CBR3 TDP1 3900/4885MAPK1 3899/4885HIF1A 1727/4885
US-11209733-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 TDP1 3327/4885MAPK1 3939/4885HIF1A 1305/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.