Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.57 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.57 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | F2 | P00734 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | RAB9A | P51151 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11673722 | 0.98 | TDP1 (0.57) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL6272290 | 0.89 | ESR1 (0.47) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| Diphenylmethanol SCHEMBL27613528 | 0.88 | ALDH1A1 (0.53) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL9296377 | 0.86 | MAPT (0.50) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL8522570 | 0.85 | TDP1 (0.61) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL8078151 | 0.85 | TDP1 (0.61) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL8522569 | 0.85 | TDP1 (0.61) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL6276758 | 0.85 | TDP1 (0.61) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL194890 | 0.83 | TDP1 (0.59) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL29930782 | 0.83 | TDP1 (0.46) | TDP1MAPK1HIF1ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 275 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016090169-A1 | INTRACELLULAR CASPASE PROBES FOR DETECTION OF APOPTOSIS AND INFLAMMATION AND KITS CONTAINING SUCH PROBES | SEED RESEARCH AND DEVELOPMENT LLC (US) | 2016-06-09 | — | — | WO | claimed |
| US-7728152-B2 | Process for producing 2-benzoyloxyacetaldehyde derivative | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2010-06-01 | — | — | US | claimed |
| US-7692033-B2 | Process for producing 2-benzoyloxyacetaldehyde derivative | DAICEL CHEMICAL INDUSTRIES, LTD. (JP) | 2010-04-06 | — | — | US | claimed |
| CN-100556886-C | Produce the method for 2-O-Benzoylglycolaldehyde derivative | DAICEL CHEM (JP) | 2009-11-04 | — | — | CN | claimed |
| US-20090192321-A1 | PROCESS FOR PRODUCING 2-BENZOYLOXYACETALDEHYDE DERIVATIVE | NISHIKAWA KAZUYOSHI | 2009-07-30 | — | — | US | claimed |
| EP-1461041-A4 | PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF ANTIVIRAL NUCLEOSIDES | PHARMASSET LTD (BB) | 2006-03-29 | — | — | EP | claimed |
| CN-1690038-A | Process for producing 2-benzoyloxyacetaldehyde derivative | DAICEL CHEM (JP) | 2005-11-02 | — | — | CN | claimed |
| US-20050234246-A1 | Process for producing 2-benzoyloxyacetaldehyde derivative | DAICEL CHEMICAL INDUSTRIES, LTD. | 2005-10-20 | — | — | US | claimed |
| CN-1620295-A | Preparation of intermediates for the synthesis of antiviral nucleosides | PHARMASSET LTD (BB) | 2005-05-25 | — | — | CN | claimed |
| US-20040254201-A1 | Substituted-1,3-oxathiolanes and substituted-1,3-dioxolanes with antiviral properties | BELLEAU BERNARD (CA) | 2004-12-16 | — | — | US | claimed |
| EP-1461041-A2 | PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF ANTIVIRAL NUCLEOSIDES | Pharmasset Ltd. (BB) | 2004-09-29 | — | — | EP | claimed |
| US-20030162992-A1 | Reacting a 2,2-dialkoxyethyl halide with an appropriate carboxylate compound to obtain acetal compound; hydrolyzing the acetal to form the alpha -acyloxyacetaldehyde | PHARMASSET, INC. | 2003-08-28 | — | — | US | claimed |
| WO-2003051298-A2 | PREPARATION OF INTERMEDIATES USEFUL IN THE SYNTHESIS OF ANTIVIRAL NUCLEOSIDES | PHARMASSET LTD. (BB) | 2003-06-26 | — | — | WO | claimed |
| US-20030087918-A1 | Synthesis of substituted 1,3-dioxolanes and substituted 1,3-oxathiolanes with antiviral properties | BIOCHEM PHARMA INC. (CA) | 2003-05-08 | — | — | US | claimed |
| US-20240124511-A1 | COMPOSITIONS AND METHODS OF MODULATING THE IMMUNE RESPONSE BY ACTIVATING ALPHA PROTEIN KINASE 1 | TIANJIN HONGKE BAISHI QIXIN VENTURE CAPITAL PARTNERSHIP (LIMITED PARTNERSHIP) (CN) | 2024-04-18 | — | — | US | disclosed |
| US-11840551-B2 | Compositions and methods of modulating the immune response by activating alpha protein kinase 1 | SHANGHAI YAO YUAN BIOTECHNOLOGY CO., LTD. (CN) | 2023-12-12 | — | — | US | disclosed |
| US-20230382925-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | VERTEX PHARMA (US) | 2023-11-30 | — | — | US | disclosed |
| US-5047407-A | 2-substituted-5-substituted-1,3-oxathiolanes with antiviral properties | IAF BIOCHEM INTERNATIONAL, INC. (CA) | 1991-09-10 | — | — | US | disclosed |
| EP-0382526-A2 | Substituted -1,3-oxathiolanes with antiviral properties | BIOCHEM PHARMA INC (CA) | 1990-08-16 | — | — | EP | disclosed |
| EP-0242863-A2 | Process for manufacturing lithographic printing plates | FUJI PHOTO FILM CO., LTD. (JP) | 1987-10-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050234246-A1 | Process for producing 2-benzoyloxyacetaldehyde derivative | ALDH1A1, ALDH2, CBR1 | TDP1 3721/4885MAPK1 1902/4885HIF1A 108/4885 |
| US-20230382925-A1 | MODULATORS OF CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR | CFTR, SCNN1G, SCNN1B | TDP1 4527/4885MAPK1 3904/4885HIF1A 3823/4885 |
| US-11840551-B2 | Compositions and methods of modulating the immune response by activating alpha protein kinase 1 | PHKA1, PHKA2, PRKCA | TDP1 1634/4885MAPK1 142/4885HIF1A 660/4885 |
| US-20030087918-A1 | Synthesis of substituted 1,3-dioxolanes and substituted 1,3-oxathiolanes with antiviral properties | IFNAR1, ZC3HAV1, NUDT1 | TDP1 559/4885MAPK1 1791/4885HIF1A 1159/4885 |
| US-20240124511-A1 | COMPOSITIONS AND METHODS OF MODULATING THE IMMUNE RESPONSE BY ACTIVATING ALPHA PROTEIN KINASE 1 | PHKA1, PHKA2, PRKCA | TDP1 1634/4885MAPK1 142/4885HIF1A 660/4885 |
| US-20090192321-A1 | PROCESS FOR PRODUCING 2-BENZOYLOXYACETALDEHYDE DERIVATIVE | ALDH1A1, ALDH2, CBR1 | TDP1 3721/4885MAPK1 1902/4885HIF1A 108/4885 |
| US-20040254201-A1 | Substituted-1,3-oxathiolanes and substituted-1,3-dioxolanes with antiviral properties | IFNAR1, ZC3HAV1, MAVS | TDP1 412/4885MAPK1 2005/4885HIF1A 1189/4885 |
| US-20030162992-A1 | Reacting a 2,2-dialkoxyethyl halide with an appropriate carboxylate compound to obtain acetal compound; hydrolyzing the acetal to form the alpha -acyloxyacetaldehyde | DERA, DPYD, DHPS | TDP1 630/4885MAPK1 3371/4885HIF1A 952/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.