Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.57 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | LMNA | P02545 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | TSHR | P16473 | 2/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | TK1 | P04183 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8522570 | 0.83 | TDP1 (0.61) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL8078151 | 0.83 | TDP1 (0.61) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL8522569 | 0.83 | TDP1 (0.61) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL6276758 | 0.83 | TDP1 (0.61) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL1030901 | 0.82 | TDP1 (0.59) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL194890 | 0.82 | TDP1 (0.59) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL1219383 | 0.80 | LMNA (0.58) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL11673722 | 0.80 | TDP1 (0.57) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| SCHEMBL28343462 | 0.80 | CYP3A4 (0.69) | TDP1MAPK1HIF1ASLC6A2SLC6A3 | |
| Benzene SCHEMBL28207781 | 0.80 | CYP3A4 (0.69) | TDP1MAPK1HIF1ASLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-103201262-B | Autotaxin inhibitors and application thereof | AMIRA PHARMACEUTICALS, INC. (US) | 2016-06-01 | — | — | CN | disclosed |
| CN-103201262-A | Autotaxin inhibitors and uses thereof | AMIRA PHARMACEUTICALS INC | 2013-07-10 | — | — | CN | disclosed |
| US-20050080113-A1 | Medicinal compositions | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2005-04-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050080113-A1 | Medicinal compositions | TNF, TRAF6, MMP8 | TDP1 3398/4885MAPK1 4/4885HIF1A 304/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.