Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC5A1 | P13866 | 1/20 | 0.35 |
| ▸ | SLC5A2 | P31639 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.33 |
| ▸ | MGLL | Q99685 | 4/20 | 0.32 |
| ▸ | CHRNA1 | P02708 | 3/20 | 0.32 |
| ▸ | CHRNB1 | P11230 | 3/20 | 0.32 |
| ▸ | CHRNB2 | P17787 | 3/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.32 |
| ▸ | CHRNB4 | P30926 | 3/20 | 0.32 |
| ▸ | CHRNA3 | P32297 | 3/20 | 0.32 |
| ▸ | CHRNA4 | P43681 | 3/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | CHRNG | P07510 | 2/20 | 0.31 |
| ▸ | CHRND | Q07001 | 2/20 | 0.31 |
| ▸ | BUB1 | O43683 | 2/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.30 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1948953 | 1.00 | SLC5A1 (0.35) | SLC5A1SLC5A2MAOBMGLLCHRNA1 | |
| SCHEMBL3145738 | 0.84 | CXCL8 (0.39) | MAOBMGLLFFAR4L3MBTL1 | |
| SCHEMBL3145731 | 0.84 | CXCL8 (0.39) | MAOBMGLLFFAR4L3MBTL1 | |
| SCHEMBL3144159 | 0.80 | PDE4D (0.36) | MAOBMGLLHDAC3HDAC1HDAC2 | |
| SCHEMBL3144157 | 0.80 | PDE4D (0.36) | MAOBMGLLHDAC3HDAC1HDAC2 | |
| SCHEMBL6211946 | 0.77 | CCR1 (0.47) | L3MBTL1ALDH1A1 | |
| SCHEMBL13486195 | 0.76 | MGLL (0.34) | MGLLL3MBTL1 | |
| SCHEMBL19859187 | 0.75 | L3MBTL1 (0.42) | SLC5A1SLC5A2FFAR4L3MBTL1ALDH1A1 | |
| SCHEMBL3204875 | 0.74 | ALDH1A1 (0.50) | L3MBTL1ALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL3141666 | 0.72 | TSHR (0.35) | MGLLHDAC2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20110136843-A1 | Novel Combination of Compounds to be Used in the Treatment of Airway Diseases, Especially Chronic Obstructive Pulmonary Disease (COPD) and Asthma | ASTRAZENECA AB (SE) | 2011-06-09 | — | — | US | disclosed |
| WO-2008096136-A1 | COMBINATIONS WITH A MUSCARINIC RECEPTOR ANTAGONIST | ARGENTA DISCOVERY LTD (GB) | 2008-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136843-A1 | Novel Combination of Compounds to be Used in the Treatment of Airway Diseases, Especially Chronic Obstructive Pulmonary Disease (COPD) and Asthma | CCR1, CCR5, CCR3 | SLC5A1 2507/4885SLC5A2 3836/4885MAOB 1343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.