Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIRT1 | Q96EB6 | 2/20 | 0.55 |
| ▸ | HDAC2 | Q92769 | 4/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.52 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.52 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19501832 | 0.90 | SIRT1 (0.70) | SIRT1HDAC2MEN1KMT2ANPC1 | |
| SCHEMBL26417130 | 0.86 | PTPN1 (0.65) | SIRT1HDAC2HDAC1HDAC3NCOR2 | |
| SCHEMBL19491398 | 0.86 | SIRT1 (0.72) | SIRT1MEN1KMT2AKDM4EPOLB | |
| SCHEMBL19491365 | 0.85 | SIRT1 (0.76) | SIRT1HDAC2HDAC1HDAC3NCOR2 | |
| SCHEMBL19501531 | 0.83 | SIRT1 (0.64) | SIRT1HDAC2HDAC1HDAC3NCOR2 | |
| SCHEMBL5082916 | 0.83 | SMN1; SMN2 (0.65) | SIRT1MEN1KMT2ANPC1RAB9A | |
| SCHEMBL19491373 | 0.82 | PTPN1 (0.69) | SIRT1HDAC2HDAC1HDAC3NCOR2 | |
| SCHEMBL19491391 | 0.81 | KMT2A (0.62) | SIRT1HDAC2HDAC1HDAC3NCOR2 | |
| SCHEMBL19491368 | 0.81 | NPC1 (0.63) | SIRT1HDAC2HDAC1HDAC3NCOR2 | |
| SCHEMBL9197688 | 0.80 | PTPN1 (0.65) | SIRT1HDAC2MEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10343438-B2 | Heat-sensitive recording material | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2019-07-09 | — | — | US | disclosed |
| US-20170297355-A1 | Heat-Sensitive Recording Material | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2017-10-19 | — | — | US | disclosed |
| US-20170297355-A1 | Heat-Sensitive Recording Material | NIPPON KAYAKU KABUSHIKI KAISHA (JP) | 2017-10-19 | — | — | US | disclosed |
| US-20150328220-A1 | METHODS OF TREATING CHRONIC KIDNEY DISEASE CHARACTERIZED BY MACROALBUMINURIA | CONCERT PHARMACEUTICALS, INC. | 2015-11-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170297355-A1 | Heat-Sensitive Recording Material | SCN1A, SCN3A, KCNN3 | SIRT1 1247/4885HDAC2 1449/4885HDAC1 1477/4885 |
| US-20150328220-A1 | METHODS OF TREATING CHRONIC KIDNEY DISEASE CHARACTERIZED BY MACROALBUMINURIA | REN, ATP6V1B1, GLS | SIRT1 537/4885HDAC2 2237/4885HDAC1 1498/4885 |
| US-10343438-B2 | Heat-sensitive recording material | SCN1A, SCN3A, KCNN3 | SIRT1 1247/4885HDAC2 1449/4885HDAC1 1477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.