SCHEMBL1949658

SCHEMBL1949658

COC(=O)C(C)Oc1cccc(C=O)c1

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SRC P12931 1/20 0.47
POLB P06746 3/20 0.47
ALDH1A1 P00352 2/20 0.47
ALDH2 P05091 1/20 0.46
NPC1 O15118 3/20 0.44
RAB9A P51151 2/20 0.44
TDP1 Q9NUW8 1/20 0.44
TSHR P16473 1/20 0.43
MAOA P21397 3/20 0.42
MAOB P27338 3/20 0.42
OGG1 O15527 1/20 0.42
KMT2A Q03164 3/20 0.42
GAA P10253 1/20 0.42
MAPT P10636 1/20 0.42
HPGD P15428 1/20 0.42
SMN1; SMN2 Q16637 1/20 0.42
KLK7 P49862 1/20 0.41
UNG P13051 1/20 0.41
MEN1 O00255 2/20 0.41
BLM P54132 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2174549 1.00 SRC (0.47) SRCPOLBALDH1A1ALDH2NPC1
SCHEMBL29342586 0.85 L3MBTL1 (0.50) SRCPOLBALDH1A1NPC1RAB9A
SCHEMBL4298184 0.84 GAA (0.51) SRCPOLBALDH1A1NPC1RAB9A
SCHEMBL1409135 0.84 GAA (0.51) SRCPOLBALDH1A1NPC1RAB9A
SCHEMBL2930425 0.84 GAA (0.51) SRCPOLBALDH1A1NPC1RAB9A
SCHEMBL3066413 0.84 SRC (0.44) SRCPOLBALDH1A1NPC1RAB9A
SCHEMBL2552258 0.83 ALDH1A1 (0.48) SRCPOLBALDH1A1NPC1RAB9A
SCHEMBL2556133 0.83 SRC (0.49) SRCPOLBALDH1A1NPC1RAB9A
SCHEMBL7835396 0.82 ALDH1A3 (0.59) POLBALDH1A1ALDH2KMT2AMAPT
SCHEMBL2560494 0.82 OGG1 (0.47) SRCPOLBALDH1A1NPC1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2507237-A1 IMIDAZOQUINOLINES WHICH ACT VIA TOLL - LIKE RECEPTORS (TLR) Dainippon Sumitomo Pharma Co., Ltd. (JP) 2012-10-10 EP disclosed
WO-2011068233-A1 IMIDAZOQUINOLINES WHICH ACT VIA TOLL - LIKE RECEPTORS (TLR) DAINIPPON SUMITOMO PHARMA CO., LTD. (JP) 2011-06-09 WO disclosed
US-20110136801-A1 Novel Compounds DAINIPPON SUMITOMO PHARMA CO. LTD. (JP) 2011-06-09 US disclosed
US-6664214-B1 Uracil compounds and use thereof SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-12-16 US disclosed
EP-0656892-B1 HERBICIDAL 2- (4-HETEROCYCLIC-PHENOXYMETHYL)PHENOXY]-ALKANOATES FMC CORP (US) 2001-06-13 EP disclosed
US-5798316-A GRASS OR BROADLEAF CONTROLLING AGENTS FMC CORPORATION 1998-08-25 US disclosed
US-5674810-A MIXTURE OF TWO HERBICIDES WITH DIFFERENT STRUCTURES, CARRIER FMC CORPORATION (US) 1997-10-07 US disclosed
WO-1997008953-A1 HERBICIDAL 2-[(4-HETEROCYCLIC-PHENOXYMETHYL)PHENOXY]-ALKANOATES FMC CORPORATION (US) 1997-03-13 WO disclosed
EP-0656892-A1 HERBICIDAL 2- (4-HETEROCYCLIC-PHENOXYMETHYL)PHENOXY]-ALKANOATES FMC CORPORATION (US) 1995-06-14 EP disclosed
US-5344812-A 1-methyl-6 -trifluoromethyl-2,4-pyrimidinedione-3-yl derivative as plant growth regulators FMC CORPORATION (US) 1994-09-06 US disclosed
CN-1083479-A 2-[(4-heterocycle-phenoxymethyl) phenoxy group] the alkanoates weedicide FMC CORP (US) 1994-03-09 CN disclosed
WO-1994004514-A1 HERBICIDAL 2-[(4-HETEROCYCLIC-PHENOXYMETHYL)PHENOXY]-ALKANOATES FMC CORPORATION (US) 1994-03-03 WO disclosed
US-5262390-A PLANT GROWTH REGULATORS FMC CORPORATION (US) 1993-11-16 US disclosed
US-3968117-A CARDIOVASCULAR BAYER AKTIENGESELLSCHAFT (DT) 1976-07-06 US disclosed
US-3959296-A CARDIOVASCULAR AGENTS BAYER AKTIENGESELLSCHAFT (DT) 1976-05-25 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110136801-A1 Novel Compounds C1R, RB1, CNKSR1 SRC 2412/4885POLB 3185/4885ALDH1A1 173/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.