Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | ALDH2 | P05091 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 3/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.42 |
| ▸ | OGG1 | O15527 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | UNG | P13051 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1949658 | 1.00 | SRC (0.47) | SRCPOLBALDH1A1ALDH2NPC1 | |
| SCHEMBL29342586 | 0.85 | L3MBTL1 (0.50) | SRCPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL4298184 | 0.84 | GAA (0.51) | SRCPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL1409135 | 0.84 | GAA (0.51) | SRCPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL2930425 | 0.84 | GAA (0.51) | SRCPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL3066413 | 0.84 | SRC (0.44) | SRCPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL2552258 | 0.83 | ALDH1A1 (0.48) | SRCPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL2556133 | 0.83 | SRC (0.49) | SRCPOLBALDH1A1NPC1RAB9A | |
| SCHEMBL7835396 | 0.82 | ALDH1A3 (0.59) | POLBALDH1A1ALDH2KMT2AMAPT | |
| SCHEMBL2560494 | 0.82 | OGG1 (0.47) | SRCPOLBALDH1A1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7973078-B2 | Sulfonamide compound or salt thereof | ASTELLAS PHARMA INC. (JP) | 2011-07-05 | — | — | US | disclosed |