Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Sulfuric Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM1 known ✓ | P11229 | 1/20 | 0.32 |
| ▸ | CHRM3 known ✓ | P20309 | 1/20 | 0.32 |
| ▸ | ACHE | P22303 | 1/20 | 0.37 |
| ▸ | ENPP2 | Q13822 | 4/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | BBOX1 | O75936 | 2/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.31 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.31 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL61004 | 0.93 | ACHE (0.42) | ACHEENPP2KDM4EMAPK1HIF1A | |
| Hydrochloric Acid SCHEMBL27571208 | 0.93 | ACHE (0.42) | ACHEENPP2KDM4EMAPK1HIF1A | |
| Sulfuric Acid SCHEMBL1950510 | 0.92 | BBOX1 (0.39) | ACHEENPP2KDM4EMAPK1HIF1A | |
| Hydrochloric Acid SCHEMBL3112798 | 0.91 | ACHE (0.41) | ACHEKDM4EMAPK1HIF1ABBOX1 | |
| Hydrochloric Acid SCHEMBL1201070 | 0.91 | ACHE (0.41) | ACHEENPP2KDM4EMAPK1HIF1A | |
| SCHEMBL25422694 | 0.91 | ACHE (0.43) | ACHEKDM4EMAPK1HIF1ABBOX1 | |
| SCHEMBL33607 | 0.91 | ACHE (0.43) | ACHEKDM4EMAPK1HIF1ABBOX1 | |
| Hydrochloric Acid SCHEMBL18141865 | 0.91 | ACHE (0.33) | ACHEENPP2KDM4EMAPK1HIF1A | |
| Sulfuric Acid SCHEMBL1950509 | 0.90 | BBOX1 (0.40) | ACHEENPP2KDM4EMAPK1HIF1A | |
| Hydrochloric Acid SCHEMBL21777097 | 0.90 | APEX1 (0.43) | ACHEKDM4EMAPK1HIF1AAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8663612-B2 | Ampholytic ter-polymers for use in personal care compositions | BASF SE (DE) | 2014-03-04 | — | — | US | claimed |
| US-20100226868-A1 | AMPHOLYTIC TER-POLYMERS FOR USE IN PERSONAL CARE COMPOSITIONS | BASF SE (DE) | 2010-09-09 | — | — | US | claimed |
| US-9469713-B2 | Ampholytic ter-polymers for use in personal care compositions | BASF SE (DE) | 2016-10-18 | — | — | US | disclosed |
| WO-2016022161-A1 | KERATIN CONDITIONING POLYMERS FOR USE IN PERSONAL CARE COMPOSITONS | BASF SE (DE) | 2016-02-11 | — | — | WO | disclosed |
| WO-2015054452-A1 | KERATIN CONDITIONING BIO-BASED POLYMERS FOR USE IN PERSONAL CARE COMPOSITIONS | BASF SE (DE) | 2015-04-16 | — | — | WO | disclosed |
| EP-2403472-B1 | AMPHOLYTIC TER-POLYMERS FOR USE IN PERSONAL CARE COMPOSITIONS | BASF SE (DE) | 2014-08-20 | — | — | EP | disclosed |
| US-8663612-B2 | Ampholytic ter-polymers for use in personal care compositions | BASF SE (DE) | 2014-03-04 | — | — | US | disclosed |
| US-20100226868-A1 | AMPHOLYTIC TER-POLYMERS FOR USE IN PERSONAL CARE COMPOSITIONS | BASF SE (DE) | 2010-09-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100226868-A1 | AMPHOLYTIC TER-POLYMERS FOR USE IN PERSONAL CARE COMPOSITIONS | KRT18, CUTA, PRKDC | CHRM1 1931/4885CHRM3 2654/4885ACHE 1327/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.