Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RX3 | P56373 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20432311 | 0.89 | P2RX3 (0.36) | P2RX3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL16028130 | 0.78 | P2RX3 (0.36) | P2RX3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL22105453 | 0.71 | MEN1 (0.35) | P2RX3MEN1KMT2A | |
| SCHEMBL18833895 | 0.69 | THRB (0.41) | P2RX3NPC1RAB9AMEN1KMT2A | |
| SCHEMBL21499674 | 0.69 | TRPC4 (0.41) | P2RX3 | |
| SCHEMBL19375462 | 0.68 | P2RX3 (0.46) | P2RX3 | |
| SCHEMBL20432337 | 0.68 | P2RX3 (0.46) | P2RX3 | |
| SCHEMBL21499666 | 0.67 | P2RX3 (0.43) | P2RX3 | |
| SCHEMBL19375035 | 0.66 | P2RX3 (0.44) | P2RX3 | |
| SCHEMBL20656224 | 0.66 | P2RX3 (0.46) | P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9969736-B2 | Substituted xanthines and methods of use thereof | HYDRA BIOSCIENCES, INC. (US) | 2018-05-15 | — | — | US | disclosed |
| US-20170305910-A1 | Substituted Xanthines and Methods of Use Thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305910-A1 | Substituted Xanthines and Methods of Use Thereof | TRPC5, TRPC7, TRPC4 | P2RX3 30/4885NPC1 988/4885RAB9A 3823/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.