Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NAAA | Q02083 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | FKBP1A | P62942 | 4/20 | 0.32 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.31 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.31 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.31 |
| ▸ | HTR2B | P41595 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | PNLIP | P16233 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19505764 | 0.91 | ALDH1A1 (0.32) | ALDH1A1NAAALMNAFKBP1APRSS1 | |
| SCHEMBL21042231 | 0.89 | ALDH1A1 (0.34) | ALDH1A1 | |
| SCHEMBL19505778 | 0.85 | NAAA (0.33) | ALDH1A1NAAALMNAFKBP1APRSS1 | |
| SCHEMBL19505781 | 0.85 | NAAA (0.33) | ALDH1A1NAAALMNAFKBP1APRSS1 | |
| SCHEMBL19506179 | 0.83 | MEN1 (0.34) | LMNAMEN1NR1I2CHRM2CYP3A4 | |
| SCHEMBL19506076 | 0.82 | MMP2 (0.35) | ALDH1A1NAAALMNAFKBP1APRSS1 | |
| SCHEMBL19506075 | 0.82 | FKBP1A (0.45) | FKBP1A | |
| SCHEMBL29593544 | 0.82 | FKBP1A (0.45) | FKBP1A | |
| SCHEMBL19505773 | 0.81 | FKBP1A (0.48) | FKBP1A | |
| SCHEMBL21042060 | 0.79 | ALDH1A1 (0.34) | ALDH1A1NR1I2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184558-A1 | NOVEL PROMYSALIN ANALOGUES AND METHODS OF USE THEREOF | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2017-10-26 | — | — | WO | disclosed |