Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FKBP1A | P62942 | 8/20 | 0.48 |
| ▸ | SPHK1 | Q9NYA1 | 9/20 | 0.40 |
| ▸ | SPHK2 | Q9NRA0 | 3/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19506075 | 0.97 | FKBP1A (0.45) | FKBP1ASPHK1SPHK2 | |
| SCHEMBL29593544 | 0.97 | FKBP1A (0.45) | FKBP1ASPHK1SPHK2 | |
| SCHEMBL21042217 | 0.89 | FKBP1A (0.42) | FKBP1A | |
| SCHEMBL19505774 | 0.87 | FKBP1A (0.44) | FKBP1ASPHK1SPHK2PIN1 | |
| SCHEMBL21042213 | 0.86 | CNR1 (0.39) | FKBP1ASPHK1SPHK2 | |
| SCHEMBL19506076 | 0.85 | MMP2 (0.35) | FKBP1A | |
| SCHEMBL19505980 | 0.84 | FKBP1A (0.41) | FKBP1ASPHK1SPHK2 | |
| SCHEMBL19505781 | 0.82 | NAAA (0.33) | FKBP1A | |
| SCHEMBL19505778 | 0.82 | NAAA (0.33) | FKBP1A | |
| SCHEMBL19505765 | 0.81 | ALDH1A1 (0.33) | FKBP1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017184558-A1 | NOVEL PROMYSALIN ANALOGUES AND METHODS OF USE THEREOF | TEMPLE UNIVERSITY-OF THE COMMONWEALTH SYSTEM OF HIGHER EDUCATION (US) | 2017-10-26 | — | — | WO | disclosed |