Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | S100A4 | P26447 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | GPR3 | P46089 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | TTR | P02766 | 1/20 | 0.39 |
| ▸ | CES1 | P23141 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CASP1 | P29466 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6974773 | 0.79 | GPR3 (0.60) | MEN1KMT2AS100A4GPR3KDM4E | |
| SCHEMBL13704120 | 0.79 | GPR3 (0.60) | CASP3MEN1KMT2APOLBGPR3 | |
| SCHEMBL22792110 | 0.79 | GPR3 (0.60) | CASP3MEN1KMT2APOLBGPR3 | |
| SCHEMBL13704044 | 0.79 | GPR3 (0.60) | CASP3MEN1KMT2APOLBGPR3 | |
| Hydrochloric Acid SCHEMBL27740780 | 0.78 | GPR3 (0.58) | MEN1KMT2AS100A4GPR3KDM4E | |
| SCHEMBL22451360 | 0.72 | GFER (0.60) | CASP3MEN1KMT2APOLBKDM4E | |
| Formamide SCHEMBL28364111 | 0.72 | GPR3 (0.51) | MEN1KMT2APOLBGPR3KDM4E | |
| SCHEMBL19255620 | 0.71 | MEN1 (0.49) | CASP3MEN1KMT2AGPR3KDM4E | |
| SCHEMBL20133640 | 0.69 | ADORA3 (0.42) | MEN1KMT2AKDM4EALDH1A1GAA | |
| SCHEMBL22623757 | 0.69 | MEN1 (0.56) | MEN1KMT2AKDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170305846-A1 | 2,2' -DIAMINOBIARYLS HAVING A PHTHALOYL GROUP OR SUCCINOYL GROUP | EVONIK DEGUSSA GMBH (DE) | 2017-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170305846-A1 | 2,2' -DIAMINOBIARYLS HAVING A PHTHALOYL GROUP OR SUCCINOYL GROUP | SUCLA2, SPATS2L, SUCLG2 | CASP3 3146/4885MEN1 1413/4885KMT2A 198/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.