Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LGMN | Q99538 | 3/20 | 0.45 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 7/20 | 0.41 |
| ▸ | GAA | P10253 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.41 |
| ▸ | HTT | P42858 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | USP2 | O75604 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28298610 | 0.84 | AKR1C3 (0.45) | LGMNMAPTSMN1; SMN2ALDH1A1HTT | |
| SCHEMBL20631 | 0.78 | MAPT (0.61) | LGMNPIK3R1PIK3CAMTORMAPT | |
| SCHEMBL19533191 | 0.78 | AKR1C3 (0.52) | MAPTGAASMN1; SMN2ALDH1A1KMT2A | |
| SCHEMBL20631313 | 0.77 | LMNA (0.61) | LGMNPIK3R1PIK3CAMTORMAPT | |
| Hydrochloric Acid SCHEMBL16209945 | 0.77 | MAPT (0.65) | LGMNPIK3R1PIK3CAMTORMAPT | |
| SCHEMBL14320289 | 0.73 | PIK3R1 (0.59) | LGMNPIK3R1PIK3CAMTORMAPT | |
| SCHEMBL13370287 | 0.73 | MAPT (0.50) | LGMNPIK3R1PIK3CAMTORMAPT | |
| SCHEMBL4386393 | 0.72 | MAPT (0.64) | LGMNPIK3R1PIK3CAMTORMAPT | |
| SCHEMBL15731795 | 0.71 | PIK3R1 (0.39) | LGMNPIK3R1PIK3CAMTORMAPT | |
| SCHEMBL19648927 | 0.69 | MAPT (0.50) | LGMNPIK3R1PIK3CAMTORMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111116553-B | Preparation method of dihydropyridone derivatives | 北京鑫开元医药科技有限公司 | 2022-02-08 | — | — | CN | claimed |
| CN-111116553-B | Preparation method of dihydropyridone derivatives | 北京鑫开元医药科技有限公司 | 2022-02-08 | — | — | CN | disclosed |
| US-20170313699-A1 | PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF | Jubilant Generics Limited (IN) | 2017-11-02 | — | — | US | disclosed |
| US-20170313699-A1 | PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF | Jubilant Generics Limited (IN) | 2017-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170313699-A1 | PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF | VKORC1, VKORC1L1, CYP4X1 | LGMN 3988/4885PIK3R1 1804/4885PIK3CA 233/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.