Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | HTT | P42858 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | LGMN | Q99538 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.38 |
| ▸ | USP2 | O75604 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19533190 | 0.84 | LGMN (0.45) | ALDH1A1MEN1MAPTHTTKMT2A | |
| SCHEMBL1432961 | 0.78 | AKR1C3 (0.65) | AKR1C3ALDH1A1MEN1MAPTHTT | |
| SCHEMBL19533191 | 0.78 | AKR1C3 (0.52) | AKR1C3ALDH1A1MEN1MAPTKMT2A | |
| SCHEMBL17642581 | 0.72 | AKR1C3 (0.57) | AKR1C3ALDH1A1MEN1MAPTHTT | |
| SCHEMBL1919863 | 0.70 | AKR1C3 (0.44) | AKR1C3ALDH1A1MEN1MAPTHTT | |
| SCHEMBL2883585 | 0.69 | LTA4H (0.67) | AKR1C3ALDH1A1MEN1MAPTHTT | |
| SCHEMBL30071064 | 0.69 | — | — | |
| SCHEMBL9093746 | 0.67 | LMNA (0.71) | ALDH1A1MEN1MAPTHTTKMT2A | |
| SCHEMBL14345952 | 0.65 | AKR1C3 (0.57) | AKR1C3ALDH1A1MEN1MAPTHTT | |
| SCHEMBL14862707 | 0.65 | AKR1C3 (0.49) | AKR1C3ALDH1A1MEN1MAPTHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109879798-A | A kind of preparation method of the important impurity of Eliquis intermediate | 山东新华制药股份有限公司 | 2019-06-14 | — | — | CN | claimed |
| CN-109879798-A | A kind of preparation method of the important impurity of Eliquis intermediate | 山东新华制药股份有限公司 | 2019-06-14 | — | — | CN | disclosed |