Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1C3 | P42330 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 8/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | BLM | P54132 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | MEN1 | O00255 | 3/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.47 |
| ▸ | SIRT6 | Q8N6T7 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.47 |
| ▸ | IDE | P14735 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL85548 | 0.82 | AKR1C3 (0.71) | AKR1C3MAPTKDM4EGAABLM | |
| SCHEMBL19533190 | 0.78 | LGMN (0.45) | MAPTKDM4EGAAKMT2AALDH1A1 | |
| SCHEMBL28298610 | 0.78 | AKR1C3 (0.45) | AKR1C3MAPTKDM4EKMT2AALDH1A1 | |
| SCHEMBL4383897 | 0.76 | MAPT (0.72) | AKR1C3MAPTKDM4EGAABLM | |
| SCHEMBL3682506 | 0.75 | AKR1C3 (0.58) | AKR1C3MAPTKDM4EGAABLM | |
| SCHEMBL1995413 | 0.75 | MAPT (0.50) | AKR1C3MAPTKDM4EGAABLM | |
| SCHEMBL20709642 | 0.75 | MAPT (0.32) | AKR1C3MAPTKDM4EGAABLM | |
| SCHEMBL3693254 | 0.74 | MAPT (0.54) | AKR1C3MAPTKDM4EGAABLM | |
| SCHEMBL9647832 | 0.74 | MITF (0.70) | AKR1C3MAPTKDM4EGAABLM | |
| SCHEMBL4690699 | 0.72 | MAPT (0.71) | AKR1C3MAPTKDM4EKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018158620-A1 | PREPARATION OF ACTIVE PHARMACEUTICAL INGREDIENTS AND INTERMEDIATES THEREOF | SUN PHARMACEUTICAL INDUSTRIES LIMITED (IN) | 2018-09-07 | — | — | WO | disclosed |
| US-20170313699-A1 | PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF | Jubilant Generics Limited (IN) | 2017-11-02 | — | — | US | disclosed |
| US-20170313699-A1 | PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF | Jubilant Generics Limited (IN) | 2017-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170313699-A1 | PROCESS FOR THE PREPARATION OF APIXABAN AND INTERMEDIATES THEREOF | VKORC1, VKORC1L1, CYP4X1 | AKR1C3 131/4885MAPT 4806/4885KDM4E 2146/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.