Sugi Predict

Sugi Predict / Compounds / SCHEMBL195372

SCHEMBL195372

SCHEMBL195372

C=C(C)C(=O)Nc1ccc2c(c1)C(=O)NC2=O

nearest known ligand 0.61

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 6/20 0.61
▸ ALDH1A1 P00352 5/20 0.61
▸ GLA P06280 1/20 0.61
▸ KMT2A Q03164 8/20 0.61
▸ HPGD P15428 3/20 0.58
▸ MEN1 O00255 5/20 0.58
▸ ALOX12 P18054 1/20 0.56
▸ CTDSP1 Q9GZU7 1/20 0.55
▸ CASP3 P42574 2/20 0.54
▸ HSD17B10 Q99714 2/20 0.52
▸ SMN1; SMN2 Q16637 1/20 0.52
▸ RXFP1 Q9HBX9 3/20 0.51
▸ PKM P14618 2/20 0.51
▸ POLB P06746 2/20 0.51
▸ MAPT P10636 1/20 0.50
▸ TDP1 Q9NUW8 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5838218 0.83 ALDH1A1 (0.69) KDM4EALDH1A1GLAKMT2AHPGD
SCHEMBL15452102 0.80 ALDH1A1 (0.62) KDM4EALDH1A1KMT2AHPGDMEN1
SCHEMBL4462900 0.78 KDM4E (0.66) KDM4EALDH1A1GLAKMT2AHPGD
SCHEMBL5947099 0.78 KDM4E (0.71) KDM4EALDH1A1GLAKMT2AHPGD
SCHEMBL13256675 0.78 MAPT (0.71) ALDH1A1KMT2AMEN1CTDSP1SMN1; SMN2
SCHEMBL26695993 0.78 KDM4E (0.65) KDM4EALDH1A1GLAKMT2AHPGD
SCHEMBL12857661 0.77 CASP3 (0.58) KDM4EALDH1A1GLAKMT2AHPGD
SCHEMBL6260912 0.76 KDM4E (1.00) KDM4EALDH1A1GLAKMT2AHPGD
SCHEMBL12635981 0.76 KMT2A (1.00) KDM4EALDH1A1GLAKMT2AHPGD
SCHEMBL439393 0.75 RXFP1 (0.74) KDM4EALDH1A1KMT2AHPGDMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 155 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20050182061-A1 Phthalimide compounds useful as protein kinase inhibitors GREEN JEREMY (US) 2005-08-18 — — US claimed
WO-2005039564-A1 PHTHALIMIDE COMPOUNDS USEFUL AS PROTEIN KINASE INHIBITORS VERTEX PHARMACEUTICALS INCORPORATED (US) 2005-05-06 — — WO claimed
US-11209734-B2 Oxime ester photoinitiators BASF SE 2021-12-28 — — US disclosed
US-11209733-B2 Oxime ester photoinitiators BASF SE 2021-12-28 — — US disclosed
US-11204554-B2 Oxime ester photoinitiators BASF SE 2021-12-21 — — US disclosed
CN-107652222-B Oxime ester photoinitiators 巴斯夫欧洲公司 2021-09-10 — — CN disclosed
EP-3019473-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2020-02-19 — — EP disclosed
US-10488756-B2 Oxime ester photoinitiators BASF SE (DE) 2019-11-26 — — US disclosed
EP-3354641-B1 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2019-07-17 — — EP disclosed
US-10234761-B2 Oxime ester photoinitiators BASF SE (DE) 2019-03-19 — — US disclosed
EP-2847167-B9 OXIME ESTER PHOTOINITIATORS BASF SE (DE) 2019-02-20 — — EP disclosed
EP-1410109-A1 PHOTOSENSITIVE RESIN COMPOSITION Ciba SC Holding AG (CH) 2004-04-21 — — EP disclosed
EP-1395615-A1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE Ciba SC Holding AG (CH) 2004-03-10 — — EP disclosed
US-6596445-B1 Initiators for photopolymerization of radically polymerizable compounds CIBA SPECIALTY CHEMICALS CORPORATION 2003-07-22 — — US disclosed
WO-2003010602-A1 PHOTOSENSITIVE RESIN COMPOSITION CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2003-02-06 — — WO disclosed
WO-2002100903-A1 OXIME ESTER PHOTOINITIATORS HAVING A COMBINED STRUCTURE CIBA SPECIALTY CHEMICALS HOLDING INC. (CH) 2002-12-19 — — WO disclosed
US-20020020832-A1 Photosensitive resin composition CIBA SPECIALTY CHEMICALS CORP. 2002-02-21 — — US disclosed
US-20010012596-A1 For resist applications; thermostability, storage stability CIBA SPECIALTY CHEMICALS CORP. 2001-08-09 — — US disclosed
CN-1305124-A Photosensitive resin composition CIBA SC HOLDING AG (CH) 2001-07-25 — — CN disclosed
US-5663212-A Light-sensitive resin composition FUJI PHOTO FILM CO., LTD. (JP) 1997-09-02 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11209734-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 KDM4E 1549/4885ALDH1A1 823/4885GLA 2702/4885
US-10488756-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 KDM4E 1549/4885ALDH1A1 823/4885GLA 2702/4885
US-20050182061-A1 Phthalimide compounds useful as protein kinase inhibitors PDK1, PDPK1, MTOR KDM4E 793/4885ALDH1A1 3870/4885GLA 3335/4885
US-11204554-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 KDM4E 1583/4885ALDH1A1 779/4885GLA 2719/4885
US-10234761-B2 Oxime ester photoinitiators C9, C5, CBR3 KDM4E 721/4885ALDH1A1 2225/4885GLA 2793/4885
US-11209733-B2 Oxime ester photoinitiators OR10J3, OXER1, QSOX1 KDM4E 1549/4885ALDH1A1 823/4885GLA 2702/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.