SCHEMBL195407

SCHEMBL195407

NP(=O)(O)ON1CCNCC1

nearest known ligand 0.33

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
ANPEP P15144 1/20 0.33
ERAP2 Q6P179 1/20 0.33
CA2 P00918 2/20 0.31
CA12 O43570 1/20 0.31
CA1 P00915 1/20 0.31
CA9 Q16790 1/20 0.31
CHKA P35790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29160731 0.82 CA2 (0.33) ANPEPERAP2CA2CA12CA1
SCHEMBL227948 0.82 CA2 (0.33) ANPEPERAP2CA2CA12CA1
SCHEMBL18584736 0.82
SCHEMBL28634205 0.82
Water SCHEMBL11853077 0.80 CA2 (0.32) ANPEPERAP2CA2CA12CA1
SCHEMBL27567916 0.79 FDPS (0.34) ANPEPERAP2
SCHEMBL28306346 0.78 CA2 (0.31) ANPEPERAP2CA2CA12CA1
Hydrochloric Acid SCHEMBL27950022 0.78 CA2 (0.31) ANPEPERAP2CA2CA12CA1
SCHEMBL11128978 0.77 CA2 (0.31) CA2CA12CA1CA9CHKA
SCHEMBL225178 0.75 FDPS (0.35)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9982261-B2 Antisense antiviral compounds and methods for treating a filovirus infection SAREPTA THERAPEUTICS, INC. (US) 2018-05-29 US disclosed
US-20170306323-A1 ANTISENSE ANTIVIRAL COMPOUNDS AND METHODS FOR TREATING A FILOVIRUS INFECTION JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2017-10-26 US disclosed
EP-2024499-B1 OLIGONUCLEOTIDE ANALOGS HAVING CATIONIC INTERSUBUNIT LINKAGES SAREPTA THERAPEUTICS INC (US) 2017-10-25 EP disclosed
EP-3205342-A1 ANTISENSE ANTIVIRAL COMPOUNDS AND METHODS FOR TREATING A FILOVIRUS INFECTION Sarepta Therapeutics, Inc. (US) 2017-08-16 EP disclosed
EP-2735568-B1 Oligonucleotide analogs having cationic intersubunit linkages AVI BIOPHARMA INC (US) 2017-08-02 EP disclosed
EP-2603220-B1 ANTISENSE ANTIVIRAL COMPOUNDS AND METHODS FOR TREATING A FILOVIRUS INFECTION SAREPTA THERAPEUTICS INC (US) 2017-03-15 EP disclosed
US-9382536-B2 Antisense antiviral compounds and methods for treating a filovirus infection SAREPTA THERAPEUTICS, INC. (US) 2016-07-05 US disclosed
US-20150275204-A1 ANTISENSE ANTIVIRAL COMPOUNDS AND METHODS FOR TREATING A FILOVIRUS INFECTION JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2015-10-01 US disclosed
EP-2735568-A1 Oligonucleotide analogs having cationic intersubunit linkages AVI BioPharma, Inc. (US) 2014-05-28 EP disclosed
US-8703735-B2 Antisense antiviral compounds and methods for treating a filovirus infection SAREPTA THERAPEUTICS, INC. (US) 2014-04-22 US disclosed
US-20090186847-A1 ANTISENSE ANTIVIRAL COMPOUNDS AND METHODS FOR TREATING A FILOVIRUS INFECTION SAREPTA THERAPEUTICS, INC. 2009-07-23 US disclosed
US-7524829-B2 Antisense antiviral compounds and methods for treating a filovirus infection AVI BIOPHARMA, INC. (US) 2009-04-28 US disclosed
US-20090088562-A1 Oligonucleotide analogs having cationic intersubunit linkages JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2009-04-02 US disclosed
US-7507196-B2 Antisense antiviral compounds and methods for treating a filovirus infection AVI BIOPHARMA, INC. (US) 2009-03-24 US disclosed
EP-2024499-A2 OLIGONUCLEOTIDE ANALOGS HAVING CATIONIC INTERSUBUNIT LINKAGES Avi Biopharma, Inc. (US) 2009-02-18 EP disclosed
WO-2008036127-A2 OLIGONUCLEOTIDE ANALOGS HAVING CATIONIC INTERSUBUNIT LINKAGES AVI BIOPHARMA, INC. (US) 2008-03-27 WO disclosed
EP-1814596-A2 ANTISENSE ANTIVIRAL COMPOUNDS AND METHODS FOR TREATING FILOVIRUS INFECTION Avi Biopharma, Inc. (US) 2007-08-08 EP disclosed
US-20060281701-A1 Antisense antiviral compounds and methods for treating a filovirus infection SAREPTA THERAPEUTICS, INC. 2006-12-14 US disclosed
US-20060205693-A1 Antisense antiviral compounds and methods for treating a filovirus infection SAREPTA THERAPEUTICS, INC. 2006-09-14 US disclosed
WO-2006050414-A2 ANTISENSE ANTIVIRAL COMPOUNDS AND METHODS FOR TREATING FILOVIRUS INFECTION AVI BIOPHARMA, INC. (US) 2006-05-11 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20170306323-A1 ANTISENSE ANTIVIRAL COMPOUNDS AND METHODS FOR TREATING A FILOVIRUS INFECTION HNRNPU, MED25, SSU72 ANPEP 353/4885ERAP2 512/4885CA2 4338/4885
US-20150275204-A1 ANTISENSE ANTIVIRAL COMPOUNDS AND METHODS FOR TREATING A FILOVIRUS INFECTION HNRNPU, MED25, SSU72 ANPEP 353/4885ERAP2 512/4885CA2 4338/4885
US-20060205693-A1 Antisense antiviral compounds and methods for treating a filovirus infection MED25, UPF1, RNGTT ANPEP 733/4885ERAP2 1506/4885CA2 4497/4885
US-20060281701-A1 Antisense antiviral compounds and methods for treating a filovirus infection UPF1, NSUN2, RNGTT ANPEP 806/4885ERAP2 1365/4885CA2 4405/4885
US-20090186847-A1 ANTISENSE ANTIVIRAL COMPOUNDS AND METHODS FOR TREATING A FILOVIRUS INFECTION RNGTT, POLM, EIF2AK2 ANPEP 372/4885ERAP2 900/4885CA2 4257/4885
US-20090088562-A1 Oligonucleotide analogs having cationic intersubunit linkages SLC38A7, SLC43A3, SLC28A3 ANPEP 569/4885ERAP2 669/4885CA2 1741/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.