Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | CAPN1 | P07384 | 2/20 | 0.44 |
| ▸ | TGM2 | P21980 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.44 |
| ▸ | F10 | P00742 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CCR4 | P51679 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14570689 | 0.85 | HTR7 (0.43) | NPC1LMNARAB9ASMN1; SMN2L3MBTL1 | |
| SCHEMBL27996446 | 0.72 | HTT (0.58) | NPC1LMNARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL1938499 | 0.70 | SMN1; SMN2 (0.55) | LMNASMN1; SMN2L3MBTL1TGM2MEN1 | |
| SCHEMBL12812726 | 0.70 | KMT2A (0.64) | NPC1LMNARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL12812906 | 0.69 | LMNA (0.56) | LMNASMN1; SMN2L3MBTL1TGM2MEN1 | |
| SCHEMBL1938810 | 0.69 | HTT (0.54) | NPC1LMNARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL1938809 | 0.69 | HTT (0.54) | NPC1LMNARAB9ASMN1; SMN2MEN1 | |
| SCHEMBL5108553 | 0.68 | HTT (0.56) | LMNASMN1; SMN2TGM2MEN1KMT2A | |
| SCHEMBL12929518 | 0.68 | F2 (0.55) | NPC1RAB9ASMN1; SMN2L3MBTL1MEN1 | |
| SCHEMBL13222773 | 0.68 | TPSAB1 (0.48) | F10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170314023-A1 | MATRIPTASE INHIBITORS AND USES THEREOF AGAINST ORTHOMYXOVIRIDAE INFECTIONS | UNIVERSITE DE SHERBROOKE (CA) | 2017-11-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170314023-A1 | MATRIPTASE INHIBITORS AND USES THEREOF AGAINST ORTHOMYXOVIRIDAE INFECTIONS | MMP7, MATR3, ADAMTS1 | NPC1 2037/4885LMNA 3418/4885RAB9A 1344/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.