Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 2/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.52 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.52 |
| ▸ | NR1H4 | Q96RI1 | 5/20 | 0.49 |
| ▸ | DHODH | Q02127 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 2/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.47 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.47 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554343 | 0.91 | KDM4E (0.53) | RAB9ANPC1MEN1ALDH1A1KMT2A | |
| SCHEMBL19554145 | 0.89 | ALDH1A1 (0.45) | RAB9ANPC1MEN1ALDH1A1KMT2A | |
| SCHEMBL19554355 | 0.84 | DHODH (0.56) | RAB9ANPC1MEN1ALDH1A1KMT2A | |
| SCHEMBL19554221 | 0.83 | KMT2A (0.64) | RAB9ANPC1MEN1ALDH1A1KMT2A | |
| SCHEMBL19554172 | 0.79 | DHODH (0.52) | RAB9ANPC1MEN1KMT2ASLC16A3 | |
| SCHEMBL19554234 | 0.79 | DHODH (0.58) | RAB9ANPC1MEN1KMT2ASLC16A3 | |
| SCHEMBL19554338 | 0.78 | SLC16A3 (0.43) | RAB9ANPC1MEN1ALDH1A1KMT2A | |
| SCHEMBL8044197 | 0.76 | DHODH (0.79) | RAB9ANPC1MEN1KMT2ASLC16A3 | |
| SCHEMBL19554206 | 0.76 | SLC16A3 (0.43) | MEN1ALDH1A1KMT2ASLC16A3NR1H4 | |
| SCHEMBL19554296 | 0.76 | KCNK2 (0.40) | RAB9ANPC1MEN1ALDH1A1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |