Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACLY | P53396 | 1/20 | 0.50 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.46 |
| ▸ | DHODH | Q02127 | 1/20 | 0.46 |
| ▸ | SERPINE1 | P05121 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | GRIK1 | P39086 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.42 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.41 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.41 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.41 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.41 |
| ▸ | ERO1A | Q96HE7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554330 | 0.85 | KCNK2 (0.46) | ACLYPRSS12DHODHMAPTMEN1 | |
| SCHEMBL19554126 | 0.84 | PRSS12 (0.47) | ACLYPRSS12DHODHSERPINE1MAPT | |
| SCHEMBL19554240 | 0.83 | STING1 (0.50) | ACLYPRSS12DHODHMAPTMEN1 | |
| SCHEMBL19554248 | 0.82 | ABL1 (0.48) | ACLYPRSS12DHODHSERPINE1MAPT | |
| SCHEMBL19554195 | 0.82 | ABL1 (0.50) | ACLYSERPINE1HDAC1 | |
| SCHEMBL19554172 | 0.81 | DHODH (0.52) | ACLYPRSS12DHODHSERPINE1MAPT | |
| SCHEMBL19554123 | 0.80 | KCNK2 (0.50) | ACLYDHODHMAPTMEN1PKM | |
| SCHEMBL19554229 | 0.79 | SERPINE1 (0.61) | SERPINE1AKR1C4AKR1C3AKR1C2AKR1C1 | |
| SCHEMBL19554338 | 0.79 | SLC16A3 (0.43) | ACLYDHODHSERPINE1MEN1PKM | |
| SCHEMBL19554206 | 0.79 | SLC16A3 (0.43) | ACLYPRSS12DHODHMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |