Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK8 | P45983 | 1/20 | 0.36 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.36 |
| ▸ | TBK1 | Q9UHD2 | 2/20 | 0.35 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.35 |
| ▸ | KMO | O15229 | 2/20 | 0.34 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.34 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.34 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.34 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.34 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.34 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.34 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.34 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | MAP3K5 | Q99683 | 1/20 | 0.32 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554255 | 0.80 | KEAP1 (0.38) | MAPK8MAPK9KMOPRKAB2PRKAG1 | |
| SCHEMBL6483619 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL19554245 | 0.75 | XDH (0.48) | XDH | |
| SCHEMBL19555101 | 0.73 | SLC22A12 (0.39) | TBK1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL19554311 | 0.72 | AKR1A1 (0.35) | MAPK8MAPK9TBK1MBOAT4 | |
| SCHEMBL19554261 | 0.72 | XDH (0.46) | MAPK8MAPK9XDHALDH1A1HPGD | |
| SCHEMBL19554322 | 0.72 | KDM4E (0.48) | ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL15320457 | 0.72 | KDM4E (0.54) | TBK1IKBKEALDH1A1HPGDKDM4E | |
| SCHEMBL19555383 | 0.71 | IRAK4 (0.37) | TBK1PRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL19554194 | 0.70 | PDE5A (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |