Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABL1 | P00519 | 2/20 | 0.48 |
| ▸ | ACLY | P53396 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | STING1 | Q86WV6 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | APEX1 | P27695 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PRSS12 | P56730 | 2/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.41 |
| ▸ | KCNK2 | O95069 | 1/20 | 0.40 |
| ▸ | GSK3A | P49840 | 1/20 | 0.40 |
| ▸ | GSK3B | P49841 | 1/20 | 0.40 |
| ▸ | DHODH | Q02127 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554195 | 0.89 | ABL1 (0.50) | ABL1ACLYALDH1A1STING1SERPINE1 | |
| SCHEMBL19554126 | 0.83 | PRSS12 (0.47) | ACLYMAPTTDP1MEN1KMT2A | |
| SCHEMBL19554330 | 0.82 | KCNK2 (0.46) | ACLYALDH1A1STING1MAPTSMN1; SMN2 | |
| SCHEMBL19554249 | 0.82 | ACLY (0.50) | ACLYMAPTTDP1MEN1KMT2A | |
| SCHEMBL19554206 | 0.81 | SLC16A3 (0.43) | ACLYALDH1A1MAPTSMN1; SMN2TDP1 | |
| SCHEMBL19554240 | 0.80 | STING1 (0.50) | ACLYSTING1KDM4EMAPTTDP1 | |
| SCHEMBL19554229 | 0.79 | SERPINE1 (0.61) | KDM4ESERPINE1KCNK2 | |
| SCHEMBL19554173 | 0.78 | KCNK2 (0.48) | ACLYMAPTTDP1MEN1KMT2A | |
| SCHEMBL19554338 | 0.78 | SLC16A3 (0.43) | ACLYALDH1A1GAAKDM4ESMN1; SMN2 | |
| SCHEMBL19554226 | 0.78 | KCNK2 (0.42) | ACLYALDH1A1KDM4EMAPTSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |