Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KEAP1 | Q14145 | 2/20 | 0.38 |
| ▸ | AKR1A1 | P14550 | 1/20 | 0.37 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
| ▸ | KMO | O15229 | 2/20 | 0.36 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.36 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.36 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.36 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.36 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.36 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.36 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | GFER | P55789 | 1/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554189 | 0.80 | AKR1A1 (0.33) | AKR1A1AKR1B1ATR | |
| SCHEMBL19554358 | 0.80 | MAPK8 (0.36) | KMOPRKAB2PRKAG1PRKAA2PRKAA1 | |
| SCHEMBL28868065 | 0.75 | PDE4D (0.51) | KDM4EMAPK8MAPK9PDE4D | |
| SCHEMBL28868070 | 0.75 | PDE4D (0.51) | KDM4EMAPK8MAPK9PDE4D | |
| SCHEMBL6990530 | 0.74 | MAPK8 (0.41) | MAPK8MAPK9PDE4D | |
| SCHEMBL7221383 | 0.74 | MAPK8 (0.41) | MAPK8MAPK9PDE4D | |
| SCHEMBL2593591 | 0.74 | RAB9A (0.55) | AKR1A1AKR1B1KMOALDH1A1KDM4E | |
| SCHEMBL19554326 | 0.73 | KDM4E (0.51) | KEAP1IDO1ALDH1A1KDM4EMAPT | |
| SCHEMBL28779927 | 0.73 | MAPK8 (0.40) | MAPK8MAPK9PDE4D | |
| SCHEMBL28779932 | 0.73 | MAPK8 (0.40) | MAPK8MAPK9PDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |