Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1A1 | P14550 | 1/20 | 0.33 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.33 |
| ▸ | ATR | Q13535 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554255 | 0.80 | KEAP1 (0.38) | AKR1A1AKR1B1ATR | |
| SCHEMBL19554250 | 0.73 | HDAC1 (0.35) | — | |
| SCHEMBL19554311 | 0.70 | AKR1A1 (0.35) | AKR1A1AKR1B1 | |
| SCHEMBL9562757 | 0.67 | KMO (0.36) | AKR1A1AKR1B1 | |
| SCHEMBL25430573 | 0.66 | POLB (0.34) | — | |
| SCHEMBL12180451 | 0.63 | SYK (0.47) | AKR1A1AKR1B1 | |
| SCHEMBL13717529 | 0.63 | FPR2 (0.41) | AKR1A1AKR1B1 | |
| SCHEMBL30679855 | 0.63 | SLC6A2 (0.33) | AKR1A1AKR1B1ATR | |
| SCHEMBL19554929 | 0.62 | AKR1A1 (0.39) | AKR1A1AKR1B1 | |
| SCHEMBL19554358 | 0.60 | MAPK8 (0.36) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |