Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 3/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.40 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19555285 | 0.91 | NPC1 (0.45) | NPC1RAB9AMAPTALDH1A1TP53 | |
| SCHEMBL19554377 | 0.91 | SMN1; SMN2 (0.51) | NPC1RAB9AMAPTALDH1A1TP53 | |
| SCHEMBL19554380 | 0.86 | MAOB (0.39) | NPC1RAB9AMAPTTP53KCNQ3 | |
| SCHEMBL19554310 | 0.84 | SMN1; SMN2 (0.38) | NPC1RAB9ASMN1; SMN2KDM4E | |
| SCHEMBL19554101 | 0.83 | CYP1A2 (0.45) | NPC1RAB9AMAPTALDH1A1TP53 | |
| SCHEMBL19554313 | 0.82 | KCNMA1 (0.42) | NPC1RAB9AMAPTSMN1; SMN2CYP1A2 | |
| SCHEMBL19554930 | 0.82 | GPR35 (0.42) | NPC1RAB9AMAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL19554379 | 0.82 | HDAC3 (0.40) | NPC1RAB9AMAPTSMN1; SMN2KDM4E | |
| SCHEMBL19554374 | 0.81 | KDM4E (0.49) | NPC1RAB9AMAPTTP53SMN1; SMN2 | |
| SCHEMBL19554232 | 0.81 | MAPT (0.45) | NPC1RAB9AMAPTALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |