Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 3/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.40 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 7/20 | 0.37 |
| ▸ | RAB9A | P51151 | 7/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554380 | 0.92 | MAOB (0.39) | HDAC3HDAC2HDAC1NPC1RAB9A | |
| SCHEMBL19554101 | 0.89 | CYP1A2 (0.45) | NPC1RAB9ASMN1; SMN2GAAKDM4E | |
| SCHEMBL19554313 | 0.88 | KCNMA1 (0.42) | HDAC3HDAC2HDAC1NPC1RAB9A | |
| SCHEMBL19555281 | 0.84 | SMN1; SMN2 (0.39) | HDAC3HDAC2HDAC1NPC1RAB9A | |
| SCHEMBL19554930 | 0.84 | GPR35 (0.42) | NPC1RAB9ASMN1; SMN2GAAKDM4E | |
| SCHEMBL19554377 | 0.84 | SMN1; SMN2 (0.51) | NPC1RAB9ASMN1; SMN2GAAKDM4E | |
| SCHEMBL19554273 | 0.82 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2GAAKDM4E | |
| SCHEMBL19554279 | 0.79 | JAK2 (0.42) | HDAC1NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL19554191 | 0.77 | GAA (0.47) | NPC1RAB9AGAAKDM4EMAPT | |
| SCHEMBL19554871 | 0.75 | F10 (0.48) | NPC1RAB9ASMN1; SMN2CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |