Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 3/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 6/20 | 0.39 |
| ▸ | RAB9A | P51151 | 6/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | CASP3 | P42574 | 1/20 | 0.37 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.37 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.37 |
| ▸ | MLLT1 | Q03111 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554168 | 0.86 | KCNMA1 (0.43) | GPR35HDAC1HDAC3HDAC2NPC1 | |
| SCHEMBL19554687 | 0.78 | KLKB1 (0.42) | GPR35HDAC1HDAC3HDAC2NPC1 | |
| SCHEMBL1307013 | 0.75 | KCNMA1 (0.56) | GPR35HDAC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL19554341 | 0.74 | HDAC3 (0.45) | HDAC3NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL1308878 | 0.73 | GPR35 (0.55) | GPR35NPC1RAB9ASMN1; SMN2CYP1A2 | |
| SCHEMBL19554123 | 0.72 | KCNK2 (0.50) | HDAC1NPC1RAB9ASMN1; SMN2GAA | |
| SCHEMBL4422766 | 0.72 | GPR35 (0.52) | GPR35HDAC1HDAC3HDAC2NPC1 | |
| SCHEMBL19554379 | 0.72 | HDAC3 (0.40) | GPR35HDAC1HDAC3HDAC2NPC1 | |
| SCHEMBL1307938 | 0.70 | GPR35 (0.53) | GPR35NPC1RAB9A | |
| SCHEMBL1307860 | 0.69 | GPR35 (0.56) | GPR35HDAC1NPC1RAB9ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |