Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.43 |
| ▸ | GPR35 | Q9HC97 | 4/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | TAS1R2 | Q8TE23 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | F10 | P00742 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK2 | P24941 | 1/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19554341 | 0.87 | HDAC3 (0.45) | KCNMA1TAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL19554352 | 0.86 | GPR35 (0.45) | GPR35SMN1; SMN2MAOBRAB9ACYP1A2 | |
| SCHEMBL6713933 | 0.81 | RXFP1 (0.41) | KCNMA1GPR35SMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL1307013 | 0.81 | KCNMA1 (0.56) | KCNMA1GPR35SMN1; SMN2LMNAL3MBTL1 | |
| SCHEMBL1308878 | 0.80 | GPR35 (0.55) | KCNMA1GPR35SMN1; SMN2L3MBTL1RAB9A | |
| SCHEMBL19555065 | 0.80 | GRIK1 (0.43) | KCNMA1TAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL5474886 | 0.78 | GRIK1 (0.44) | SMN1; SMN2LMNARAB9A | |
| SCHEMBL19554208 | 0.78 | NOTUM (0.44) | KCNMA1TAS1R3TAS1R1TAS1R2SMN1; SMN2 | |
| SCHEMBL6708921 | 0.77 | ALOX15 (0.51) | ALOX15 | |
| SCHEMBL1307860 | 0.76 | GPR35 (0.56) | KCNMA1GPR35RAB9ACYP1A2CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | claimed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |
| WO-2017192304-A1 | ARYLCARBOXAMIDES AND USES THEREOF | INCEPTION 1, INC. (US) | 2017-11-09 | — | — | WO | disclosed |