Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | CYP17A1 | P05093 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PLD1 | Q13393 | 1/20 | 0.33 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | PANK3 | Q9H999 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30160609 | 1.00 | RAB9A (0.38) | RAB9ASMN1; SMN2MAPTIRAK4NPC1 | |
| SCHEMBL20337257 | 0.84 | IRAK4 (0.43) | RAB9ASMN1; SMN2MAPTIRAK4NPC1 | |
| SCHEMBL19554783 | 0.80 | — | — | |
| SCHEMBL20337284 | 0.76 | CTSK (0.36) | RAB9ASMN1; SMN2MAPTNPC1ALDH1A1 | |
| SCHEMBL20337115 | 0.76 | SIGMAR1 (0.38) | SMN1; SMN2MAPTALDH1A1THRBTDP1 | |
| SCHEMBL23329611 | 0.75 | CNR1 (0.34) | — | |
| SCHEMBL30160326 | 0.75 | CNR1 (0.34) | — | |
| SCHEMBL20337120 | 0.75 | GFER (0.32) | RAB9ASMN1; SMN2MAPTIRAK4NPC1 | |
| SCHEMBL20337156 | 0.75 | CYP1A2 (0.35) | RAB9ASMN1; SMN2MAPTIRAK4NPC1 | |
| SCHEMBL20337124 | 0.75 | PIK3CD (0.35) | RAB9ASMN1; SMN2IRAK4NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 20 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230131903-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-27 | — | — | US | disclosed |
| US-20230131903-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-27 | — | — | US | disclosed |
| US-20230131903-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-04-27 | — | — | US | disclosed |
| US-20230002359-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-01-05 | — | — | US | disclosed |
| US-20230002359-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2023-01-05 | — | — | US | disclosed |
| WO-2021083936-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | SYNGENTA CROP PROTECTION AG (CH) | 2021-05-06 | — | — | WO | disclosed |
| CN-109311841-B | Heteroaryl-1, 2, 4-triazole and heteroaryl-tetrazole compounds for controlling ectoparasites | 瑞士伊兰科动物保健有限公司 | 2021-04-27 | — | — | CN | disclosed |
| US-10981897-B2 | Heteroaryl-1,2,4-triazole and heteroaryl-tetrazole compounds for controlling ectoparasites | ELANCO TIERGESUNDHEIT AG (US) | 2021-04-20 | — | — | US | disclosed |
| US-10981897-B2 | Heteroaryl-1,2,4-triazole and heteroaryl-tetrazole compounds for controlling ectoparasites | ELANCO TIERGESUNDHEIT AG (US) | 2021-04-20 | — | — | US | disclosed |
| EP-3452460-B1 | HETEROARYL-1,2,4-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS FOR CONTROLLING ECTOPARASITES | ELANCO TIERGESUNDHEIT AG (CH) | 2020-02-12 | — | — | EP | disclosed |
| US-20190256501-A1 | HETEROARYL-1,2,4-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS FOR CONTROLLING ECTOPARASITES | ELANCO TIERGESUNDHEIT AG (US) | 2019-08-22 | — | — | US | disclosed |
| US-20190256501-A1 | HETEROARYL-1,2,4-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS FOR CONTROLLING ECTOPARASITES | ELANCO TIERGESUNDHEIT AG (US) | 2019-08-22 | — | — | US | disclosed |
| US-10287276-B2 | Heteroaryl-1,2,4-triazole and heteroaryl-tetrazole compounds for controlling ectoparasites | ELANCO TIERGESUNDHEIT AG (CH) | 2019-05-14 | — | — | US | disclosed |
| US-10287276-B2 | Heteroaryl-1,2,4-triazole and heteroaryl-tetrazole compounds for controlling ectoparasites | ELANCO TIERGESUNDHEIT AG (CH) | 2019-05-14 | — | — | US | disclosed |
| EP-3452460-A1 | HETEROARYL-1,2,4-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS FOR CONTROLLING ECTOPARASITES | Elanco Tiergesundheit AG (CH) | 2019-03-13 | — | — | EP | disclosed |
| CN-109311841-A | Heteroaryl-1, 2, 4-triazole and heteroaryl-tetrazole compounds for controlling ectoparasites | 瑞士伊兰科动物保健有限公司 | 2019-02-05 | — | — | CN | disclosed |
| US-20180186778-A1 | HETEROARYL-1,2,4-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS FOR CONTROLLING ECTOPARASITES | ELANCO TIERGESUNDHEIT AG (CH) | 2018-07-05 | — | — | US | disclosed |
| US-20180186778-A1 | HETEROARYL-1,2,4-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS FOR CONTROLLING ECTOPARASITES | ELANCO TIERGESUNDHEIT AG (CH) | 2018-07-05 | — | — | US | disclosed |
| US-20180186778-A1 | HETEROARYL-1,2,4-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS FOR CONTROLLING ECTOPARASITES | ELANCO TIERGESUNDHEIT AG (CH) | 2018-07-05 | — | — | US | disclosed |
| WO-2017192385-A1 | HETEROARYL-1,2,4-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS FOR CONTROLLING ECTOPARASITES | ELANCO TIERGESUNDHEIT AG (CH) | 2017-11-09 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10981897-B2 | Heteroaryl-1,2,4-triazole and heteroaryl-tetrazole compounds for controlling ectoparasites | CBR3, HRH4, H1-5 | RAB9A 2562/4885SMN1; SMN2 4745/4885MAPT 4783/4885 |
| US-20230131903-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | DDT, ACHE, GSTO1 | RAB9A 1157/4885SMN1; SMN2 875/4885MAPT 194/4885 |
| US-10287276-B2 | Heteroaryl-1,2,4-triazole and heteroaryl-tetrazole compounds for controlling ectoparasites | CBR3, HRH4, H1-5 | RAB9A 2562/4885SMN1; SMN2 4745/4885MAPT 4783/4885 |
| US-20190256501-A1 | HETEROARYL-1,2,4-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS FOR CONTROLLING ECTOPARASITES | CBR3, HRH4, H1-5 | RAB9A 2562/4885SMN1; SMN2 4745/4885MAPT 4783/4885 |
| US-20180186778-A1 | HETEROARYL-1,2,4-TRIAZOLE AND HETEROARYL-TETRAZOLE COMPOUNDS FOR CONTROLLING ECTOPARASITES | CBR3, HRH4, H1-5 | RAB9A 2562/4885SMN1; SMN2 4745/4885MAPT 4783/4885 |
| US-20230002359-A1 | PESTICIDALLY ACTIVE FUSED BICYCLIC HETEROAROMATIC COMPOUNDS | DDT, ACHE, GSTO1 | RAB9A 1020/4885SMN1; SMN2 960/4885MAPT 283/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.