Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | REN | P00797 | 8/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.45 |
| ▸ | PSMB9 | P28065 | 3/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 3/20 | 0.45 |
| ▸ | PSMB1 | P20618 | 2/20 | 0.45 |
| ▸ | PSMB10 | P40306 | 1/20 | 0.44 |
| ▸ | PSMB2 | P49721 | 1/20 | 0.44 |
| ▸ | CTSS | P25774 | 2/20 | 0.44 |
| ▸ | CTSL | P07711 | 1/20 | 0.44 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | CTSK | P43235 | 1/20 | 0.44 |
| ▸ | CDYL2 | Q8N8U2 | 1/20 | 0.43 |
| ▸ | CDYL | Q9Y232 | 1/20 | 0.43 |
| ▸ | KLK7 | P49862 | 1/20 | 0.43 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16576488 | 0.91 | PAX8 (0.53) | ATMKMT2ARENPAX8TDP1 | |
| SCHEMBL16576487 | 0.80 | REN (0.50) | ATMKMT2ARENPAX8TDP1 | |
| SCHEMBL19749811 | 0.80 | REN (0.53) | RENPAX8TDP1CTSSCTSL | |
| SCHEMBL10668564 | 0.78 | KMT2A (0.59) | ATMKMT2APAX8TDP1PSMB8 | |
| SCHEMBL13702233 | 0.78 | ACE (0.59) | ATMKMT2APAX8TDP1PSMB8 | |
| SCHEMBL16908988 | 0.78 | ACE (0.59) | ATMKMT2APAX8TDP1PSMB8 | |
| SCHEMBL13956678 | 0.77 | PAX8 (0.52) | PAX8TDP1PSMB8PSMB9PSMB5 | |
| SCHEMBL19559859 | 0.77 | REN (0.42) | ATMKMT2ARENPSMB8PSMB9 | |
| SCHEMBL22961954 | 0.77 | CTSS (0.55) | RENPAX8TDP1PSMB8PSMB9 | |
| SCHEMBL10135741 | 0.76 | CTSK (0.55) | KMT2APAX8TDP1PSMB8PSMB9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3044204-B1 | A PHOTOLABILE LINKER FOR THE SOLID-PHASE SYNTHESIS OF HYDRAZIDES AND PYRANOPYRAZOLES | UNIV DANMARKS TEKNISKE (DK) | 2017-11-08 | — | — | EP | disclosed |