Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 4/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1928970 | 0.76 | — | — | |
| SCHEMBL25633196 | 0.76 | — | — | |
| SCHEMBL25113273 | 0.72 | ALDH1A1 (0.34) | — | |
| SCHEMBL986628 | 0.72 | OPRM1 (0.34) | IRAK4 | |
| SCHEMBL989317 | 0.72 | DPP4 (0.37) | — | |
| SCHEMBL988738 | 0.72 | DPP4 (0.37) | — | |
| SCHEMBL897563 | 0.72 | OPRM1 (0.34) | IRAK4 | |
| SCHEMBL897562 | 0.72 | OPRM1 (0.34) | IRAK4 | |
| SCHEMBL988739 | 0.72 | DPP4 (0.37) | — | |
| SCHEMBL24127614 | 0.71 | RAB9A (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2791139-B1 | SUBSTITUTED HETEROCYCLIC COMPOUNDS AS TROPOMYOSIN RECEPTOR KINASE A (TRKA) INHIBITORS | Dr Reddys Laboratories Ltd (IN) | 2017-11-08 | — | — | EP | disclosed |