Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25113273 | 0.79 | ALDH1A1 (0.34) | — | |
| SCHEMBL19562614 | 0.71 | GPR119 (0.35) | — | |
| SCHEMBL22995951 | 0.64 | — | — | |
| SCHEMBL29316595 | 0.62 | HTR6 (0.49) | RAB9A | |
| SCHEMBL21078296 | 0.62 | RAB9A (0.39) | RAB9A | |
| SCHEMBL15223506 | 0.62 | NCF1 (0.37) | — | |
| SCHEMBL22988889 | 0.60 | LMNA (0.33) | — | |
| SCHEMBL20842192 | 0.60 | LMNA (0.35) | RAB9A | |
| SCHEMBL21548010 | 0.60 | CHRM2 (0.42) | — | |
| SCHEMBL513994 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021257736-A1 | METHODS FOR DELAYING, PREVENTING, AND TREATING ACQUIRED RESISTANCE TO RAS INHIBITORS | Revolution Medicines, Inc. (US) | 2021-12-23 | — | — | WO | disclosed |