Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | HRH1 | P35367 | 2/20 | 0.33 |
| ▸ | HTR2B | P41595 | 2/20 | 0.33 |
| ▸ | HTR2C | P28335 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | OGFRL1 | Q5TC84 | 1/20 | 0.32 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | GABRP | O00591 | 1/20 | 0.31 |
| ▸ | GABRD | O14764 | 1/20 | 0.31 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.31 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.31 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.31 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.31 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24127614 | 0.79 | RAB9A (0.32) | — | |
| SCHEMBL1978680 | 0.78 | ALDH1A1 (0.44) | ALDH1A1HTR2AHRH1HTR2BHTR2C | |
| Hydrochloric Acid SCHEMBL23293911 | 0.76 | ALDH1A1 (0.47) | ALDH1A1HTR2AHRH1HTR2BHTR2C | |
| SCHEMBL30226610 | 0.74 | ALDH1A1 (0.46) | ALDH1A1TSHRKDM4ECYP2C19LMNA | |
| SCHEMBL3273017 | 0.74 | OGFRL1 (0.46) | ALDH1A1TSHRKDM4ECYP2C19LMNA | |
| SCHEMBL19562614 | 0.72 | GPR119 (0.35) | — | |
| SCHEMBL321188 | 0.72 | OGFRL1 (0.48) | ALDH1A1KDM4EOGFRL1 | |
| Hydrochloric Acid SCHEMBL4151575 | 0.72 | ALDH1A1 (0.49) | ALDH1A1TSHRKDM4ECYP2C19LMNA | |
| SCHEMBL4155085 | 0.69 | TSHR (0.61) | ALDH1A1HTR2AHRH1HTR2BHTR2C | |
| SCHEMBL31334651 | 0.69 | CHRM1 (0.45) | ALDH1A1LMNACHRM1L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4234031-A2 | C40-, C28-, AND C-32-LINKED RAPAMYCIN ANALOGS AS MTOR INHIBITORS | Revolution Medicines, Inc. (US) | 2023-08-30 | — | — | EP | disclosed |
| EP-3788049-B1 | C40-, C28-, AND C-32-LINKED RAPAMYCIN ANALOGS AS MTOR INHIBITORS | REVOLUTION MEDICINES INC (US) | 2023-03-29 | — | — | EP | disclosed |