SCHEMBL1956403

SCHEMBL1956403

Nc1cccc(S(=O)(=O)Nc2ccccc2C(=O)O)c1

nearest known ligand 0.66

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.66
KMT2A Q03164 5/20 0.66
GAA P10253 1/20 0.66
POLB P06746 3/20 0.64
KDM4E B2RXH2 2/20 0.64
ALDH1A1 P00352 5/20 0.59
LMNA P02545 2/20 0.59
HSD17B10 Q99714 2/20 0.59
TDP1 Q9NUW8 2/20 0.55
TP53 P04637 1/20 0.55
SLC25A1 P53007 1/20 0.55
ACLY P53396 1/20 0.55
METAP2 P50579 1/20 0.55
PMM2 O15305 1/20 0.54
HCRTR1 O43613 1/20 0.54
G6PD P11413 1/20 0.54
PKM P14618 1/20 0.54
IDE P14735 1/20 0.54
MPI P34949 1/20 0.54
GFER P55789 1/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5470332 0.89 ALDH1A1 (0.60) MEN1KMT2AGAAPOLBKDM4E
SCHEMBL1466906 0.85 ALDH1A1 (0.72) MEN1KMT2AGAAPOLBKDM4E
SCHEMBL15822907 0.84 ALDH1A1 (0.68) MEN1KMT2AGAAPOLBKDM4E
SCHEMBL11026493 0.83 MEN1 (0.72) MEN1KMT2AGAAPOLBKDM4E
SCHEMBL6417385 0.83 MEN1 (0.72) MEN1KMT2AGAAPOLBKDM4E
SCHEMBL23200342 0.82 MEN1 (0.66) MEN1KMT2AGAAPOLBKDM4E
SCHEMBL17978501 0.81 POLB (0.62) MEN1KMT2AGAAPOLBALDH1A1
SCHEMBL11410794 0.81 MEN1 (0.73) MEN1KMT2AGAAPOLBKDM4E
SCHEMBL2331658 0.81 MEN1 (0.63) MEN1KMT2AGAAPOLBKDM4E
SCHEMBL2605789 0.81 MEN1 (0.78) MEN1KMT2AGAAPOLBKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2332998-B1 Solvent free aqueous polyurethane dispersions and methods of making and using the same VERSUM MAT US LLC (US) 2018-09-26 EP disclosed
US-9617453-B2 Solvent free aqueous polyurethane dispersions and methods of making and using the same AIR PRODUCTS AND CHEMICALS, INC. (US) 2017-04-11 US disclosed
US-20110306724-A1 Solvent Free Aqueous Polyurethane Dispersions and Methods of Making and Using the Same AIR PRODUCTS AND CHEMICALS, INC. (US) 2011-12-15 US disclosed
EP-2332998-A1 Solvent free aqueous polyurethane dispersions and methods of making and using the same Air Products and Chemicals, Inc. (US) 2011-06-15 EP disclosed
US-5693737-A POLYETHERURETHANES FOR PREPARING CREASE-RESISTANT TEXTILES BAYER AKTIENGESELLSCHAFT (DE) 1997-12-02 US disclosed
US-5607482-A BLOCKED POLYISOCYANATE BAYER AKTIENGESELLSCHAFT (DE) 1997-03-04 US disclosed
US-5508370-A POLYETHERURETHANE COPOLYMER; TEXTILE FINISH BAYER AKTIENGESELLSCHAFT (DE) 1996-04-16 US disclosed
US-5166232-A CELLULOSE/PLASTIC BLENDS, A PROCESS FOR THEIR PRODUCTION AND THEIR USE WOLFF WALSRODE AKTIENGESELLSCHAFT (DE) 1992-11-24 US disclosed
US-4544683-A GYPSUM-POLYURETHANE OR POLYURETHANE-POLYUREA BAYER AKTIENGESELLSCHAFT (DE) 1985-10-01 US disclosed
US-4382943-A DIHYDROCYCLOPENTA/C//1/BENZOPYRAN-4-/1H/ONES BOEHRINGER MANNHEIM GMBH (DE) 1983-05-10 US disclosed
US-4324716-A -POLYURETHANE FOAMS BAYER AKTIENGESELLSCHAFT (DE) 1982-04-13 US disclosed
US-4310449-A Process for the preparation of stable dispersions BAYER AKTIENGESELLSCHAFT (DE) 1982-01-12 US disclosed
US-4305858-A Process for the preparation of stable ionic dispersions of polyisocyanate-polyaddition products in hydroxyl containing compounds BAYER AKTIENGESELLSCHAFT (DE) 1981-12-15 US disclosed
US-4197219-A Aqueous polyurethane-phenolic-formaldehyde resin emulsions for use as adhesives, primers and surface coatings LORD CORPORATION (US) 1980-04-08 US disclosed
US-4147680-A Production of polyurethane resins using as active hydrogen material a stable dispersion of ionic polyisocyanate-polyaddition products in hydroxyl containing compounds as a dispersing agent BAYER AKTIENGESELLSCHAFT (DE) 1979-04-03 US disclosed
US-3970601-A COATINGS BAYER AKTIENGESELLSCHAFT (DT) 1976-07-20 US disclosed