Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 7/20 | 0.66 |
| ▸ | KMT2A | Q03164 | 7/20 | 0.66 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.65 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.65 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 2/20 | 0.62 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | PGR | P06401 | 1/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | GLO1 | Q04760 | 1/20 | 0.56 |
| ▸ | SLC40A1 | Q9NP59 | 1/20 | 0.56 |
| ▸ | PTGES2 | Q9H7Z7 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | KAT6A | Q92794 | 1/20 | 0.55 |
| ▸ | WDR5 | P61964 | 1/20 | 0.55 |
| ▸ | PGAM1 | P18669 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23200347 | 0.90 | KEAP1 (0.65) | MEN1KMT2AKEAP1NFE2L2SLC16A3 | |
| SCHEMBL3555853 | 0.87 | KEAP1 (0.56) | MEN1KMT2AKEAP1NFE2L2SLC16A3 | |
| SCHEMBL12200959 | 0.86 | CYP2C9 (0.61) | MEN1KMT2AKEAP1NFE2L2SLC16A3 | |
| SCHEMBL3560551 | 0.85 | KEAP1 (0.54) | MEN1KMT2AKEAP1NFE2L2SLC16A3 | |
| SCHEMBL2477690 | 0.85 | LMNA (0.70) | MEN1KMT2AKEAP1NFE2L2SLC16A3 | |
| SCHEMBL30486834 | 0.85 | LMNA (0.70) | MEN1KMT2AKEAP1NFE2L2SLC16A3 | |
| SCHEMBL3557703 | 0.84 | KEAP1 (0.53) | MEN1KMT2AKEAP1NFE2L2SLC16A3 | |
| SCHEMBL3988508 | 0.83 | METAP2 (0.74) | KEAP1NFE2L2SLC16A3KDM4EPGR | |
| SCHEMBL12200777 | 0.83 | FFAR4 (0.64) | MEN1KMT2AKEAP1NFE2L2SLC16A3 | |
| SCHEMBL6417385 | 0.82 | MEN1 (0.72) | MEN1KMT2AGAAKDM4EPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12065421-B2 | Inhibitors of oplophorus luciferase-derived bioluminescent complexes | PROMEGA CORPORATION (US) | 2024-08-20 | — | — | US | disclosed |
| EP-4140991-B1 | INHIBITORS OF OPLOPHORUS LUCIFERASE-DERIVED BIOLUMINESCENT COMPLEXES | PROMEGA CORP (US) | 2024-05-15 | — | — | EP | disclosed |
| EP-4140991-A1 | INHIBITORS OF OPLOPHORUS LUCIFERASE-DERIVED BIOLUMINESCENT COMPLEXES | Promega Corporation (US) | 2023-03-01 | — | — | EP | disclosed |
| US-20220365086-A1 | INHIBITORS OF OPLOPHORUS LUCIFERASE-DERIVED BIOLUMINESCENT COMPLEXES | PROMEGA CORPORATION | 2022-11-17 | — | — | US | disclosed |
| EP-3802514-B1 | INHIBITORS OF OPLOPHORUS LUCIFERASE-DERIVED BIOLUMINESCENT COMPLEXES | PROMEGA CORP (US) | 2022-08-03 | — | — | EP | disclosed |
| US-11390599-B2 | Inhibitors of oplophorus luciferase-derived bioluminescent complexes | PROMEGA CORPORATION (US) | 2022-07-19 | — | — | US | disclosed |
| EP-3802514-A1 | INHIBITORS OF OPLOPHORUS LUCIFERASE-DERIVED BIOLUMINESCENT COMPLEXES | Promega Corporation (US) | 2021-04-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20220365086-A1 | INHIBITORS OF OPLOPHORUS LUCIFERASE-DERIVED BIOLUMINESCENT COMPLEXES | LUC7L2, LYPLAL1, GUSB | MEN1 2157/4885KMT2A 2984/4885KEAP1 449/4885 |
| US-12065421-B2 | Inhibitors of oplophorus luciferase-derived bioluminescent complexes | LUC7L2, LYPLAL1, GUSB | MEN1 2157/4885KMT2A 2984/4885KEAP1 449/4885 |
| US-11390599-B2 | Inhibitors of oplophorus luciferase-derived bioluminescent complexes | LUC7L2, LYPLAL1, GUSB | MEN1 2157/4885KMT2A 2984/4885KEAP1 449/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.